C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 2 receptor, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100385 IL2RB 9606 - 22:37125838-37175054 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216223 IL2RB-001 37125838-37149990 protein_coding
  ENST00000429622 IL2RB-005 37137685-37175054 protein_coding
  ENST00000440958 IL2RB-002 37139143-37143621 nonsense_mediated_decay
  ENST00000445595 IL2RB-008 37142450-37175054 protein_coding
  ENST00000453962 IL2RB-006 37136365-37175054 protein_coding
  ENST00000461607 IL2RB-004 37139072-37175054 retained_intron
  ENST00000483573 IL2RB-003 37128522-37136408 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastHeartKidneyLiverLungOvaryTestisENST00000216223ENST00000453962ENST00000461607ENST00000483573
Transcript ID Adrenal Brain Breast Heart Kidney Liver Lung Ovary Testis
ENST00000216223 5.750±0.00 0.032±0.00 N/A 0.272±0.00 0.297±0.16 0.118±0.00 4.080±3.74 0.862±0.18 0.114±0.00
ENST00000453962 N/A N/A 0.784±0.00 N/A N/A N/A N/A N/A N/A
ENST00000461607 N/A 0.046±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000483573 N/A N/A 0.562±0.00 N/A 1.189±0.00 0.816±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036P CIL_00036P_0001 CGP 22:37065436-37175054
CIL_00036M CIL_00036M_0001 CGP 22:37125838-37199385

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004911 IDA interleukin-2 receptor activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006461 TAS protein complex assembly
GO:0007165 TAS signal transduction
GO:0009897 ISS external side of plasma membrane
GO:0016020 IDA membrane
GO:0016032 IEA viral process
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0019976 ISS interleukin-2 binding
GO:0038110 TAS interleukin-2-mediated signaling pathway
GO:0043066 IDA negative regulation of apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075720 il2rb interleukin 2 receptor, beta protein_coding Danio_rerio
ENSMUSG00000068227 Il2rb interleukin 2 receptor, beta chain protein_coding Mus_musculus

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