C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoenolpyruvate carboxykinase 2 (mitochondrial)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100889 PCK2 9606 + 14:24094053-24110598 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216780 PCK2-002 24094138-24104130 protein_coding
  ENST00000396973 PCK2-001 24094159-24100562 protein_coding
  ENST00000545054 PCK2-008 24094301-24104030 protein_coding
  ENST00000557969 PCK2-010 24102675-24103722 retained_intron
  ENST00000558096 PCK2-007 24094377-24104130 protein_coding
  ENST00000558674 PCK2-006 24094313-24100303 retained_intron
  ENST00000559171 PCK2-009 24100149-24110598 protein_coding
  ENST00000559250 PCK2-003 24094053-24104125 protein_coding
  ENST00000559503 PCK2-011 24098512-24102830 nonsense_mediated_decay
  ENST00000559584 PCK2-015 24094357-24098228 nonsense_mediated_decay
  ENST00000559837 PCK2-013 24094194-24099108 protein_coding
  ENST00000560106 PCK2-014 24094281-24098591 nonsense_mediated_decay
  ENST00000560657 PCK2-016 24094350-24097063 processed_transcript
  ENST00000560736 PCK2-012 24094150-24099125 protein_coding
  ENST00000561050 PCK2-004 24094311-24100243 retained_intron
  ENST00000561286 PCK2-005 24094311-24104124 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216780ENST00000396973ENST00000545054ENST00000558096ENST00000559250ENST00000559503ENST00000559837ENST00000560736ENST00000561286
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216780 9.240±0.00 N/A 25.945±0.00 N/A 2.782±1.14 4.009±1.12 0.521±0.00 51.803±43.56 47.027±0.00 2.301±0.00 1.738±0.00 2.469±1.23 2.510±1.50 N/A
ENST00000396973 N/A N/A N/A N/A N/A N/A 0.283±0.23 N/A N/A 0.793±0.00 N/A 1.764±0.00 N/A N/A
ENST00000545054 5.730±0.00 N/A N/A 1.889±0.00 2.205±0.00 1.574±0.00 N/A 18.472±0.00 0.771±0.00 2.330±0.00 N/A 5.919±4.27 3.149±0.00 8.696±6.29
ENST00000558096 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.142±0.00 N/A
ENST00000559250 N/A 4.194±0.00 N/A 0.402±0.00 N/A N/A 0.309±0.00 N/A N/A 1.183±0.00 N/A N/A N/A N/A
ENST00000559503 N/A N/A N/A 0.313±0.00 N/A N/A N/A N/A N/A N/A 1.101±0.00 N/A N/A N/A
ENST00000559837 N/A N/A N/A 0.458±0.00 N/A N/A N/A N/A 0.897±0.00 N/A N/A 1.292±0.00 N/A N/A
ENST00000560736 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.685±0.00 N/A N/A
ENST00000561286 15.565±0.00 4.891±0.00 N/A 0.898±0.00 4.037±1.68 5.251±0.00 0.531±0.35 28.712±0.00 49.892±0.00 3.595±0.00 N/A 3.300±1.05 N/A 5.872±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003F9 CIL_0003F9_0001 CGP 14:24070837-24115014
CIL_0003F6 CIL_0003F6_0001 CGP 14:24080107-24115014

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004611 TAS:IEA phosphoenolpyruvate carboxykinase activity
GO:0004613 IEA phosphoenolpyruvate carboxykinase (GTP) activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0005975 TAS carbohydrate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006090 IEA pyruvate metabolic process
GO:0006094 IEA gluconeogenesis
GO:0006107 IEA oxaloacetate metabolic process
GO:0006116 IEA NADH oxidation
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0017076 IEA purine nucleotide binding
GO:0032024 IEA positive regulation of insulin secretion
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0051384 IEA response to glucocorticoid
GO:0070062 IDA extracellular vesicular exosome
GO:0071333 IEA cellular response to glucose stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020956 pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) protein_coding Danio_rerio
ENSMUSG00000040618 Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) protein_coding Mus_musculus

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