C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine kinase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101213 PTK6 9606 - 20:63528001-63537370 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000217185 PTK6-201 63528425-63537370 protein_coding
  ENST00000542869 PTK6-001 63528001-63537354 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000217185ENST00000542869
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000217185 0.150±0.00 N/A 0.031±0.00 N/A 2.290±0.00 1.405±0.00 N/A N/A N/A 1.101±0.00 0.020±0.00 5.261±4.53 0.120±0.02 0.020±0.00
ENST00000542869 0.088±0.00 0.632±0.00 N/A 0.289±0.21 1.393±0.78 1.326±0.32 0.058±0.00 0.293±0.24 0.377±0.20 0.465±0.13 N/A 3.048±2.26 0.100±0.00 0.355±0.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005ZJ CIL_0005ZJ_0002 CGP 20:63520724-63537370
CIL_00045G CIL_00045G_0001 CGP 20:63528001-63547504

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004715 IDA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006468 TAS protein phosphorylation
GO:0010976 IMP positive regulation of neuron projection development
GO:0016020 IEA membrane
GO:0016477 IDA cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0042503 IDA tyrosine phosphorylation of Stat3 protein
GO:0042506 IDA tyrosine phosphorylation of Stat5 protein
GO:0042802 IPI identical protein binding
GO:0045926 IEA negative regulation of growth
GO:0046777 IMP protein autophosphorylation
GO:0060575 IEA intestinal epithelial cell differentiation
GO:0061099 IDA negative regulation of protein tyrosine kinase activity
GO:0071300 IMP cellular response to retinoic acid

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017947 ptk6a PTK6 protein tyrosine kinase 6a protein_coding Danio_rerio
ENSDARG00000059956 ptk6b PTK6 protein tyrosine kinase 6b protein_coding Danio_rerio
ENSMUSG00000038751 Ptk6 PTK6 protein tyrosine kinase 6 protein_coding Mus_musculus

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