C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: E2F transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101412 E2F1 9606 - 20:33675487-33686404 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343380 E2F1-001 33675683-33686404 protein_coding
  ENST00000622594 E2F1-201 33675487-33686404 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343380ENST00000622594
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343380 0.960±0.00 2.897±0.00 2.654±2.29 1.758±1.36 1.213±0.00 0.972±0.00 0.400±0.21 0.152±0.00 0.930±0.71 0.334±0.14 10.728±12.35 3.876±2.00 10.967±1.56
ENST00000622594 N/A N/A N/A N/A N/A 0.015±0.00 N/A N/A N/A N/A 0.117±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00003O CIL_00003O_0001 CGP 20:33666498-33686404
CIL_0001NZ CIL_0001NZ_0001 CGP 20:33675487-33720319

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000077 IMP DNA damage checkpoint
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000278 TAS mitotic cell cycle
GO:0001047 IDA core promoter binding
GO:0003677 IMP DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA:IEA regulation of transcription, DNA-templated
GO:0006915 TAS apoptotic process
GO:0007219 TAS Notch signaling pathway
GO:0007283 IEA spermatogenesis
GO:0008134 IPI transcription factor binding
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010628 IDA positive regulation of gene expression
GO:0030900 IEA forebrain development
GO:0035189 IDA Rb-E2F complex
GO:0043276 IEA anoikis
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048146 IMP positive regulation of fibroblast proliferation
GO:0048255 IDA mRNA stabilization
GO:0051726 IEA regulation of cell cycle
GO:0071398 IEA cellular response to fatty acid
GO:0071456 IEA cellular response to hypoxia
GO:0071930 IMP negative regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0072332 IEA intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1990086 IEA lens fiber cell apoptotic process
GO:2000045 IMP regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079349 E2F1 E2F transcription factor 1 protein_coding Danio_rerio
ENSMUSG00000027490 E2f1 E2F transcription factor 1 protein_coding Mus_musculus

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