C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: WAP four-disulfide core domain 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101443 WFDC2 9606 + 20:45469706-45481532 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000217425 WFDC2-003 45469756-45479748 protein_coding
  ENST00000339946 WFDC2-005 45469756-45481532 protein_coding
  ENST00000342873 WFDC2-006 45479439-45481532 protein_coding
  ENST00000372676 WFDC2-002 45469706-45481532 protein_coding
  ENST00000447118 WFDC2-004 45469756-45481531 nonsense_mediated_decay
  ENST00000462062 WFDC2-001 45471273-45481532 processed_transcript
  ENST00000488143 WFDC2-007 45479439-45481532 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000217425ENST00000339946ENST00000342873ENST00000372676ENST00000447118ENST00000462062
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000217425 N/A N/A N/A N/A N/A 0.670±0.00 N/A N/A N/A N/A N/A 2.960±0.00 N/A N/A
ENST00000339946 N/A N/A N/A N/A N/A N/A N/A 85.265±0.00 0.287±0.00 1.052±0.00 N/A N/A N/A 0.414±0.00
ENST00000342873 N/A N/A N/A N/A 0.841±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.301±0.00
ENST00000372676 0.811±0.00 12.614±0.00 2.139±0.00 0.523±0.00 6.469±4.06 54.598±0.00 0.212±0.00 307.076±0.00 1.178±0.00 221.648±0.00 1.101±0.00 84.972±64.28 2.313±0.20 147.820±0.00
ENST00000447118 0.216±0.00 N/A N/A 1.643±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.192±0.00
ENST00000462062 N/A N/A N/A 1.576±0.00 N/A N/A 0.101±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006IJ CIL_0006IJ_0001 CGP 20:45416077-45481532
CIL_0003L2 CIL_0003L2_0001 CGP 20:45469706-45515624

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004866 TAS endopeptidase inhibitor activity
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0004869 IEA cysteine-type endopeptidase inhibitor activity
GO:0005576 IEA extracellular region
GO:0005615 TAS extracellular space
GO:0006508 TAS proteolysis
GO:0007283 TAS spermatogenesis
GO:0010466 IEA negative regulation of peptidase activity
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0019828 IEA aspartic-type endopeptidase inhibitor activity
GO:0030414 IEA peptidase inhibitor activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000017723 Wfdc2 WAP four-disulfide core domain 2 protein_coding Mus_musculus

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