C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear factor of activated T-cells 5, tonicity-responsive
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102908 NFAT5 9606 + 16:69565094-69704666 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000349945 NFAT5-201 69565966-69704665 protein_coding
  ENST00000354436 NFAT5-001 69565984-69704666 protein_coding
  ENST00000393742 NFAT5-002 69566208-69704666 protein_coding
  ENST00000426654 NFAT5-004 69565094-69704650 nonsense_mediated_decay
  ENST00000562429 NFAT5-008 69676895-69690976 retained_intron
  ENST00000563474 NFAT5-011 69653236-69684916 nonsense_mediated_decay
  ENST00000565301 NFAT5-007 69647132-69696578 protein_coding
  ENST00000566899 NFAT5-006 69566351-69695676 protein_coding
  ENST00000567239 NFAT5-009 69566062-69697840 protein_coding
  ENST00000567990 NFAT5-003 69566026-69686075 nonsense_mediated_decay
  ENST00000568832 NFAT5-010 69690544-69692053 retained_intron

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000349945ENST00000354436ENST00000393742ENST00000426654ENST00000566899ENST00000567239
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000349945 N/A N/A 2.110±0.00 0.868±0.00 N/A N/A 1.074±0.00 N/A N/A N/A 0.420±0.00 0.450±0.15 0.502±0.00 0.994±0.00
ENST00000354436 2.296±0.00 0.736±0.00 6.456±0.00 2.242±0.67 2.105±0.23 0.969±0.13 0.777±0.00 1.168±0.76 4.470±0.00 4.791±0.00 1.259±0.00 1.919±1.32 0.579±0.09 2.206±0.24
ENST00000393742 2.160±0.00 0.640±0.00 N/A 2.455±0.00 2.568±0.00 2.405±0.00 N/A N/A 0.394±0.00 11.924±0.00 0.861±0.00 2.552±0.00 N/A N/A
ENST00000426654 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.092±0.00 N/A N/A
ENST00000566899 N/A N/A N/A 1.779±0.00 N/A N/A 0.831±0.00 N/A 3.043±0.00 N/A N/A N/A N/A N/A
ENST00000567239 N/A N/A N/A N/A N/A N/A 0.634±0.00 1.366±0.00 N/A N/A 0.875±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008KB CIL_0008KB_0001 VISTA 16:69347064-69947578
CIL_0004I1 CIL_0004I1_0001 CGP 16:69565094-69726951

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001816 IEA cytokine production
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0007165 NAS signal transduction
GO:0007588 TAS excretion
GO:0010628 IEA positive regulation of gene expression
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0070884 IEA regulation of calcineurin-NFAT signaling cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014022 NFAT5 (1 of 2) nuclear factor of activated T-cells 5, tonicity-responsive protein_coding Danio_rerio
ENSDARG00000020872 nfat5 nuclear factor of activated T-cells 5, tonicity-responsive protein_coding Danio_rerio
ENSMUSG00000003847 Nfat5 nuclear factor of activated T cells 5 protein_coding Mus_musculus

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