C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102978 POLR2C 9606 + 16:57462387-57472010 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219252 POLR2C-001 57462387-57472010 protein_coding
  ENST00000562599 POLR2C-005 57462669-57469198 nonsense_mediated_decay
  ENST00000562953 POLR2C-006 57462667-57470269 retained_intron
  ENST00000563115 POLR2C-002 57462660-57469903 retained_intron
  ENST00000563589 POLR2C-003 57465723-57469270 retained_intron
  ENST00000564626 POLR2C-004 57462777-57463512 retained_intron
  ENST00000564651 POLR2C-008 57462674-57470271 processed_transcript
  ENST00000567982 POLR2C-007 57462676-57470408 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000219252
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000219252 16.906±0.00 23.154±0.00 4.280±0.00 17.777±8.02 12.430±6.97 13.523±4.62 24.108±0.00 21.703±13.61 12.717±7.54 13.169±5.38 15.142±9.91 26.514±12.51 28.176±5.90 27.326±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003ZD CIL_0003ZD_0001 CGP 16:57447425-57472010
CIL_000163 CIL_000163_0001 CGP 16:57462387-57487327

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0001055 IBA RNA polymerase II activity
GO:0003677 IEA DNA binding
GO:0003899 IEA DNA-directed RNA polymerase activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005665 IDA DNA-directed RNA polymerase II, core complex
GO:0005737 IDA cytoplasm
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006289 TAS nucleotide-excision repair
GO:0006351 IEA transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006370 TAS 7-methylguanosine mRNA capping
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0015630 IDA microtubule cytoskeleton
GO:0016032 TAS viral process
GO:0046983 IEA protein dimerization activity
GO:0050434 TAS positive regulation of viral transcription

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033596 polr2c polymerase (RNA) II (DNA directed) polypeptide C protein_coding Danio_rerio
ENSMUSG00000031783 Polr2c polymerase (RNA) II (DNA directed) polypeptide C protein_coding Mus_musculus

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