C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: WAP four-disulfide core domain 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103175 WFDC1 9606 + 16:84294646-84329851 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219454 WFDC1-001 84294646-84329851 protein_coding
  ENST00000567056 WFDC1-003 84316057-84329842 retained_intron
  ENST00000568638 WFDC1-002 84294846-84329840 protein_coding
  ENST00000613603 WFDC1-005 84294944-84295492 protein_coding
  ENST00000622779 WFDC1-004 84325664-84329840 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000219454ENST00000567056ENST00000568638ENST00000613603ENST00000622779
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000219454 1.451±0.00 2.602±0.00 0.892±0.00 1.669±0.01 1.675±0.19 3.914±2.24 0.668±0.00 3.076±2.39 4.320±3.43 7.287±6.89 0.120±0.00 1.949±1.04 30.080±4.04 13.360±9.01
ENST00000567056 N/A N/A 0.063±0.00 N/A 0.080±0.00 N/A 0.012±0.00 N/A N/A 0.220±0.00 N/A 0.216±0.00 N/A 0.296±0.00
ENST00000568638 0.555±0.00 3.714±0.00 N/A 2.990±2.46 0.579±0.09 14.767±0.00 0.188±0.00 7.015±0.00 1.950±0.16 7.716±6.54 0.707±0.00 2.079±2.47 49.436±25.95 16.223±14.82
ENST00000613603 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.582±0.00 N/A N/A
ENST00000622779 N/A N/A 0.046±0.00 N/A 0.193±0.00 0.103±0.00 0.038±0.00 N/A N/A N/A N/A 0.095±0.00 N/A 0.401±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006H5 CIL_0006H5_0001 CGP 16:84218667-84329851
CIL_0007IQ CIL_0007IQ_0001 CGP 16:84294646-84464187

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0003674 ND molecular_function
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005576 IEA extracellular region
GO:0005615 NAS extracellular space
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0030308 NAS negative regulation of cell growth
GO:0030414 IEA peptidase inhibitor activity
GO:0032355 IEA response to estradiol
GO:0042493 IEA response to drug
GO:0050680 IEA negative regulation of epithelial cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058003 wfdc1 WAP four-disulfide core domain 1 protein_coding Danio_rerio
ENSMUSG00000023336 Wfdc1 WAP four-disulfide core domain 1 protein_coding Mus_musculus

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