C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pyrroline-5-carboxylate reductase-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104524 PYCRL 9606 - 8:143603913-143609773 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000220966 PYCRL-001 143603913-143609614 protein_coding
  ENST00000377579 PYCRL-002 143605547-143609773 protein_coding
  ENST00000433751 PYCRL-004 143605486-143609569 protein_coding
  ENST00000447926 PYCRL-005 143605335-143609569 nonsense_mediated_decay
  ENST00000462036 PYCRL-007 143606116-143608449 protein_coding
  ENST00000482616 PYCRL-006 143606468-143609557 retained_intron
  ENST00000495276 PYCRL-008 143604219-143609574 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000220966ENST00000433751ENST00000447926ENST00000462036ENST00000482616ENST00000495276
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000220966 0.510±0.00 2.062±0.00 N/A N/A 1.192±0.00 0.463±0.00 0.538±0.00 0.753±0.45 N/A 0.144±0.00 N/A 0.334±0.00 0.576±0.15 0.559±0.00
ENST00000433751 N/A N/A 0.264±0.00 N/A N/A N/A N/A N/A 0.179±0.00 0.150±0.00 N/A N/A N/A N/A
ENST00000447926 N/A N/A N/A N/A N/A N/A N/A 0.627±0.00 N/A N/A N/A N/A N/A N/A
ENST00000462036 N/A N/A N/A N/A N/A N/A 0.606±0.00 N/A 0.586±0.00 N/A N/A N/A N/A N/A
ENST00000482616 N/A N/A N/A N/A N/A N/A N/A 0.292±0.00 N/A 0.304±0.00 N/A N/A N/A N/A
ENST00000495276 0.857±0.00 2.350±0.00 0.083±0.00 3.483±0.00 0.725±0.67 0.168±0.00 N/A 3.414±0.00 2.321±2.23 0.638±0.43 0.397±0.00 6.746±1.24 2.541±0.07 2.642±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008C2 CIL_0008C2_0001 VISTA 8:143231340-143832399
CIL_0002GN CIL_0002GN_0001 CGP 8:143603913-143618048

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004735 IEA pyrroline-5-carboxylate reductase activity
GO:0005515 IEA protein binding
GO:0006561 IEA proline biosynthetic process
GO:0042802 IEA identical protein binding
GO:0055114 IEA oxidation-reduction process
GO:0055129 IEA L-proline biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015236 pycrl pyrroline-5-carboxylate reductase-like protein_coding Danio_rerio
ENSMUSG00000022571 Pycrl pyrroline-5-carboxylate reductase-like protein_coding Mus_musculus

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