C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutathione reductase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104687 GSR 9606 - 8:30678061-30727926 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000221130 GSR-001 30678061-30727926 protein_coding
  ENST00000521479 GSR-002 30696405-30727010 protein_coding
  ENST00000523295 GSR-004 30681931-30727667 nonsense_mediated_decay
  ENST00000537535 GSR-005 30679520-30727835 protein_coding
  ENST00000541648 GSR-006 30679520-30727835 protein_coding
  ENST00000546342 GSR-007 30679520-30727835 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000221130ENST00000521479ENST00000523295ENST00000537535ENST00000541648ENST00000546342
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000221130 7.197±0.00 5.987±0.00 1.125±0.00 5.090±3.57 1.892±0.97 6.339±1.92 6.975±4.94 23.844±19.89 18.300±0.00 6.563±4.37 9.454±0.00 8.571±2.71 10.353±2.17 7.815±3.34
ENST00000521479 N/A N/A 5.579±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000523295 N/A N/A N/A N/A 3.503±0.00 N/A N/A N/A 2.991±0.00 N/A N/A N/A N/A N/A
ENST00000537535 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.867±0.00 N/A N/A N/A
ENST00000541648 4.077±0.00 N/A N/A 4.837±0.00 N/A N/A N/A N/A N/A N/A N/A 4.943±0.00 7.577±0.00 3.699±0.00
ENST00000546342 5.265±0.00 4.948±0.00 5.251±0.00 N/A 5.506±0.00 3.917±0.20 4.822±3.74 N/A 6.329±0.00 5.279±0.00 6.556±0.00 N/A 3.026±0.00 4.295±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008IH CIL_0008IH_0001 VISTA 8:30111104-30714589

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004362 TAS:IEA glutathione-disulfide reductase activity
GO:0005739 IEA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0005829 TAS cytosol
GO:0006749 IEA glutathione metabolic process
GO:0009055 TAS electron carrier activity
GO:0009897 IEA external side of plasma membrane
GO:0015949 TAS nucleobase-containing small molecule interconversion
GO:0016491 IEA oxidoreductase activity
GO:0016668 IEA oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
GO:0044281 TAS small molecule metabolic process
GO:0045454 IEA cell redox homeostasis
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019236 gsr glutathione reductase protein_coding Danio_rerio
ENSMUSG00000031584 Gsr glutathione reductase protein_coding Mus_musculus

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