C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor necrosis factor receptor superfamily, member 10a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104689 TNFRSF10A 9606 - 8:23190452-23225126 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000221132 TNFRSF10A-001 23190452-23225126 protein_coding
  ENST00000519862 TNFRSF10A-003 23191814-23197273 retained_intron
  ENST00000524158 TNFRSF10A-002 23199886-23224600 protein_coding
  ENST00000613472 TNFRSF10A-201 23191649-23225061 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000221132ENST00000613472
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000221132 7.109±0.00 2.709±0.00 0.349±0.00 0.777±0.00 2.016±0.99 2.588±1.42 0.646±0.16 1.480±0.21 0.638±0.13 5.143±4.33 N/A 5.534±5.08 2.873±0.25 0.903±0.66
ENST00000613472 N/A N/A N/A 0.043±0.00 N/A N/A N/A 1.039±0.00 N/A N/A 0.375±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0004872 NAS receptor activity
GO:0005035 TAS death receptor activity
GO:0005515 IPI:IEA protein binding
GO:0006915 NAS apoptotic process
GO:0007165 TAS:IEA signal transduction
GO:0007250 NAS activation of NF-kappaB-inducing kinase activity
GO:0008134 IPI transcription factor binding
GO:0008625 NAS extrinsic apoptotic signaling pathway via death domain receptors
GO:0016021 IC integral component of membrane
GO:0036462 IDA TRAIL-activated apoptotic signaling pathway
GO:0045569 NAS:IEA TRAIL binding
GO:0071260 IEP cellular response to mechanical stimulus
GO:0097191 IDA extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004392 hdr hematopoietic death receptor protein_coding Danio_rerio
ENSDARG00000004451 tnfrsfa tumor necrosis factor receptor superfamily, member a protein_coding Danio_rerio
ENSMUSG00000022074 Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b protein_coding Mus_musculus

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