C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 2, catalytic subunit, beta isozyme
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104695 PPP2CB 9606 - 8:30774457-30814314 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000221138 PPP2CB-001 30785610-30812872 protein_coding
  ENST00000518243 PPP2CB-008 30793962-30812878 protein_coding
  ENST00000518532 PPP2CB-003 30786109-30791563 retained_intron
  ENST00000518564 PPP2CB-002 30785616-30812597 protein_coding
  ENST00000520056 PPP2CB-010 30794198-30810276 protein_coding
  ENST00000520334 PPP2CB-004 30790990-30794281 protein_coding
  ENST00000520500 PPP2CB-007 30799581-30814314 processed_transcript
  ENST00000522113 PPP2CB-006 30786129-30786488 processed_transcript
  ENST00000523023 PPP2CB-009 30774457-30791280 nonsense_mediated_decay
  ENST00000523804 PPP2CB-005 30793116-30794490 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000221138ENST00000518243ENST00000518564ENST00000520056
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000221138 26.727±0.00 19.060±0.00 1.394±0.00 55.286±41.79 21.869±17.35 25.637±20.23 16.891±13.83 78.849±0.00 13.038±5.04 42.266±35.32 12.274±7.30 34.467±24.67 42.290±7.50 44.976±16.35
ENST00000518243 N/A N/A 2.405±0.00 N/A N/A N/A 2.455±0.00 5.634±0.00 N/A 7.896±0.00 5.396±0.00 N/A N/A N/A
ENST00000518564 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 52.078±0.00 99.947±0.00 76.203±0.00
ENST00000520056 N/A N/A N/A 6.495±0.00 N/A N/A N/A N/A N/A N/A 3.977±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000159 TAS protein phosphatase type 2A complex
GO:0000775 IEA chromosome, centromeric region
GO:0004721 IEA phosphoprotein phosphatase activity
GO:0004722 TAS protein serine/threonine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0006470 TAS protein dephosphorylation
GO:0008022 IEA protein C-terminus binding
GO:0008152 IEA metabolic process
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008637 IEA apoptotic mitochondrial changes
GO:0010468 IEA regulation of gene expression
GO:0016311 IEA dephosphorylation
GO:0016787 IEA hydrolase activity
GO:0034976 IEA response to endoplasmic reticulum stress
GO:0042542 IEA response to hydrogen peroxide
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0046580 IEA negative regulation of Ras protein signal transduction
GO:0046677 IEA response to antibiotic
GO:0046872 IEA metal ion binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053020 ppp2cb protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform protein_coding Danio_rerio
ENSMUSG00000009630 Ppp2cb protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform protein_coding Mus_musculus

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