C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: minichromosome maintenance complex component 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104738 MCM4 9606 + 8:47960185-47978160 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262105 MCM4-001 47960936-47978160 protein_coding
  ENST00000517709 MCM4-013 47969686-47971444 retained_intron
  ENST00000518221 MCM4-008 47960185-47962327 protein_coding
  ENST00000518382 MCM4-015 47971432-47975835 nonsense_mediated_decay
  ENST00000518680 MCM4-012 47969025-47970735 processed_transcript
  ENST00000519138 MCM4-010 47961857-47966320 retained_intron
  ENST00000519170 MCM4-009 47961497-47964665 protein_coding
  ENST00000519470 MCM4-019 47970509-47971470 retained_intron
  ENST00000520637 MCM4-011 47964592-47970758 protein_coding
  ENST00000520934 MCM4-007 47960952-47962149 retained_intron
  ENST00000520994 MCM4-006 47960949-47961586 retained_intron
  ENST00000521151 MCM4-018 47975298-47977259 retained_intron
  ENST00000521261 MCM4-017 47973692-47975785 retained_intron
  ENST00000523853 MCM4-014 47971324-47973065 retained_intron
  ENST00000523944 MCM4-004 47960898-47978160 protein_coding
  ENST00000524086 MCM4-005 47960958-47962406 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262105ENST00000517709ENST00000518382ENST00000519138ENST00000519170ENST00000519470ENST00000520637ENST00000523944
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262105 3.023±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.589±0.00 N/A N/A N/A 13.636±0.00
ENST00000517709 N/A N/A N/A N/A 2.512±0.00 N/A N/A N/A 1.889±0.00 N/A N/A N/A N/A N/A
ENST00000518382 N/A N/A N/A N/A N/A N/A N/A 7.291±0.00 N/A N/A 14.876±0.00 N/A N/A N/A
ENST00000519138 N/A N/A 3.004±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 25.518±0.00 38.461±0.00 71.310±0.00
ENST00000519170 N/A N/A 3.100±0.00 N/A 5.284±0.00 N/A N/A 5.142±0.00 N/A N/A N/A N/A N/A N/A
ENST00000519470 N/A N/A N/A 10.620±0.00 N/A N/A 7.011±0.00 N/A 4.326±0.00 N/A 9.633±0.00 N/A N/A N/A
ENST00000520637 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.574±0.00 20.624±0.00 25.959±0.00 43.546±0.00
ENST00000523944 N/A 0.722±0.00 N/A 5.731±2.12 1.422±0.64 3.891±3.29 2.945±1.23 7.767±0.00 0.899±0.03 1.134±0.01 0.766±0.00 5.485±2.99 11.673±1.69 10.924±1.50

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0003677 IEA DNA binding
GO:0003678 IEA DNA helicase activity
GO:0003697 IEA single-stranded DNA binding
GO:0004003 IDA ATP-dependent DNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006260 NAS:IEA DNA replication
GO:0006268 IEA DNA unwinding involved in DNA replication
GO:0006270 IEA DNA replication initiation
GO:0006271 TAS DNA strand elongation involved in DNA replication
GO:0015979 IEA photosynthesis
GO:0015995 IEA chlorophyll biosynthetic process
GO:0016020 IDA membrane
GO:0016851 IEA magnesium chelatase activity
GO:0016887 IEA ATPase activity
GO:0042555 IDA MCM complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040041 mcm4 MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000022673 Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) protein_coding Mus_musculus

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