C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mediator complex subunit 25
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104973 MED25 9606 + 19:49818279-49838816 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000312865 MED25-001 49818289-49836979 protein_coding
  ENST00000538643 MED25-012 49818342-49836962 protein_coding
  ENST00000593595 MED25-020 49818282-49818882 retained_intron
  ENST00000593636 MED25-003 49818289-49819950 retained_intron
  ENST00000593767 MED25-023 49835058-49838816 protein_coding
  ENST00000594998 MED25-009 49832884-49836979 retained_intron
  ENST00000595185 MED25-016 49818342-49836962 protein_coding
  ENST00000599722 MED25-021 49830843-49832415 retained_intron
  ENST00000612791 MED25-201 49818342-49836962 protein_coding
  ENST00000612854 MED25-202 49818279-49836980 protein_coding
  ENST00000617849 MED25-203 49818279-49836980 protein_coding
  ENST00000618715 MED25-204 49818342-49836962 protein_coding
  ENST00000620467 MED25-205 49818279-49836980 protein_coding
  ENST00000622046 MED25-206 49832884-49836976 protein_coding
  ENST00000622402 MED25-207 49818279-49836980 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000312865ENST00000538643ENST00000618715
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000312865 20.323±0.00 24.285±0.00 25.035±0.00 25.164±0.00 17.539±0.00 13.076±0.00 25.644±0.00 6.935±0.00 26.678±0.00 39.604±0.00 48.556±21.40 26.943±1.24 58.575±0.80
ENST00000538643 N/A N/A N/A N/A N/A N/A N/A 2.925±0.00 N/A N/A N/A N/A N/A
ENST00000618715 N/A N/A N/A N/A N/A N/A 4.057±0.00 N/A N/A 24.605±19.33 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0005515 IPI protein binding
GO:0005654 TAS nucleoplasm
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0008134 IPI transcription factor binding
GO:0008219 IEA cell death
GO:0010467 TAS gene expression
GO:0035563 IMP positive regulation of chromatin binding
GO:0042974 IPI retinoic acid receptor binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046965 IPI retinoid X receptor binding
GO:0048147 IMP negative regulation of fibroblast proliferation
GO:0071158 IMP positive regulation of cell cycle arrest
GO:2001178 IMP positive regulation of mediator complex assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038005 med25 mediator of RNA polymerase II transcription, subunit 25 homolog (yeast) protein_coding Danio_rerio
ENSMUSG00000002968 Med25 mediator complex subunit 25 protein_coding Mus_musculus

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