C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BCL2 binding component 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105327 BBC3 9606 - 19:47220822-47232766 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300880 BBC3-005 47220824-47232766 protein_coding
  ENST00000341983 BBC3-002 47220824-47232766 protein_coding
  ENST00000439096 BBC3-003 47220827-47231194 protein_coding
  ENST00000449228 BBC3-001 47220824-47232766 protein_coding
  ENST00000598636 BBC3-006 47221645-47227189 retained_intron
  ENST00000601438 BBC3-004 47220822-47222568 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000300880ENST00000341983ENST00000439096ENST00000449228ENST00000598636ENST00000601438
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000300880 N/A 0.555±0.00 0.043±0.00 1.051±0.00 0.263±0.00 N/A 0.174±0.00 N/A N/A N/A N/A 1.131±0.00 0.865±0.00 0.301±0.00
ENST00000341983 N/A N/A N/A N/A N/A 0.312±0.00 N/A N/A 0.066±0.00 N/A N/A 0.984±0.00 N/A N/A
ENST00000439096 3.706±0.00 2.057±0.00 N/A 0.270±0.00 2.308±0.00 4.217±0.00 0.765±0.00 1.347±0.00 0.468±0.00 26.409±0.00 11.923±0.00 6.419±1.41 2.445±1.33 1.697±0.21
ENST00000449228 N/A N/A N/A N/A 0.467±0.00 N/A 0.102±0.00 0.152±0.00 N/A N/A N/A 1.730±0.00 0.848±0.00 N/A
ENST00000598636 N/A N/A N/A N/A 0.669±0.00 N/A N/A 0.233±0.00 N/A N/A N/A N/A N/A N/A
ENST00000601438 N/A 0.286±0.00 N/A 0.122±0.00 N/A 0.336±0.00 N/A N/A 0.282±0.00 0.477±0.00 1.260±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008G1 CIL_0008G1_0001 VISTA 19:46806794-47408636

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001836 IDA release of cytochrome c from mitochondria
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005741 TAS mitochondrial outer membrane
GO:0005829 TAS cytosol
GO:0006915 TAS apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0008340 ISS determination of adult lifespan
GO:0032464 IDA positive regulation of protein homooligomerization
GO:0032471 IDA negative regulation of endoplasmic reticulum calcium ion concentration
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0043525 ISS positive regulation of neuron apoptotic process
GO:0045926 IMP negative regulation of growth
GO:0051209 IDA release of sequestered calcium ion into cytosol
GO:0070059 ISS intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070245 ISS positive regulation of thymocyte apoptotic process
GO:0071456 IEP cellular response to hypoxia
GO:0090200 IDA positive regulation of release of cytochrome c from mitochondria
GO:0097190 IDA apoptotic signaling pathway
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:0097194 IDA execution phase of apoptosis
GO:1900740 IDA positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:2001056 ISS positive regulation of cysteine-type endopeptidase activity
GO:2001244 IMP positive regulation of intrinsic apoptotic signaling pathway

Homologs

No Homologs available.

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