C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoinositide-3-kinase, regulatory subunit 2 (beta)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105647 PIK3R2 9606 + 19:18153118-18170540 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222254 PIK3R2-001 18153118-18170540 protein_coding
  ENST00000426902 PIK3R2-002 18155622-18170073 nonsense_mediated_decay
  ENST00000459743 PIK3R2-006 18168498-18169152 retained_intron
  ENST00000464016 PIK3R2-009 18166276-18169231 nonsense_mediated_decay
  ENST00000474310 PIK3R2-004 18160867-18161468 retained_intron
  ENST00000600533 PIK3R2-010 18162046-18162717 retained_intron
  ENST00000617130 PIK3R2-201 18155880-18169294 protein_coding
  ENST00000617642 PIK3R2-202 18155880-18166140 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000222254ENST00000426902ENST00000617130
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000222254 7.102±0.00 9.661±0.00 N/A 27.605±0.00 9.142±0.00 12.869±0.00 10.672±0.00 9.139±6.82 4.570±3.52 5.882±0.00 23.488±12.91 15.573±1.07 13.700±6.25
ENST00000426902 N/A N/A 4.774±0.00 2.612±0.00 N/A 1.319±0.00 N/A N/A 1.105±0.00 1.352±0.00 N/A N/A 3.652±0.00
ENST00000617130 N/A N/A N/A N/A N/A 4.038±0.00 1.440±0.00 N/A N/A 0.532±0.00 26.706±2.71 12.515±0.00 10.095±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004E1 CIL_0004E1_0002 CGP 19:18097793-18170540

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0005942 IEA phosphatidylinositol 3-kinase complex
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0007165 IEA signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007596 TAS blood coagulation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0016303 ISS 1-phosphatidylinositol-3-kinase activity
GO:0030971 IPI receptor tyrosine kinase binding
GO:0035014 IEA phosphatidylinositol 3-kinase regulator activity
GO:0036092 ISS phosphatidylinositol-3-phosphate biosynthetic process
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043551 IEA regulation of phosphatidylinositol 3-kinase activity
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0050852 TAS T cell receptor signaling pathway
GO:0050900 TAS leukocyte migration
GO:0051056 TAS regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018060 pik3r2 phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 protein_coding Danio_rerio
ENSMUSG00000031834 Pik3r2 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) protein_coding Mus_musculus

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