C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tissue factor pathway inhibitor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105825 TFPI2 9606 - 7:93885397-93890991 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222543 TFPI2-001 93885397-93890991 protein_coding
  ENST00000451238 TFPI2-003 93886434-93890170 protein_coding
  ENST00000461482 TFPI2-002 93889918-93890753 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000222543ENST00000451238ENST00000461482
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000222543 2.404±0.00 0.148±0.00 0.243±0.00 0.078±0.00 2.491±0.00 0.621±0.09 0.302±0.08 1.190±0.20 0.763±0.61 2.748±1.25 N/A 4.179±4.35 142.878±48.62 0.282±0.22
ENST00000451238 7.023±0.00 0.964±0.00 1.451±0.00 0.522±0.00 3.986±2.06 1.082±0.28 0.652±0.09 3.441±0.34 2.014±1.18 9.377±0.00 0.147±0.00 3.788±1.93 237.152±58.74 0.860±0.51
ENST00000461482 N/A N/A N/A N/A N/A 2.077±0.00 0.688±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004SV CIL_0004SV_0002 CGP 7:93885397-93928610

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005201 TAS extracellular matrix structural constituent
GO:0005576 IEA extracellular region
GO:0005578 TAS proteinaceous extracellular matrix
GO:0005634 IDA nucleus
GO:0007596 IEA blood coagulation
GO:0010466 IEA negative regulation of peptidase activity
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0030414 IEA peptidase inhibitor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061351 tfpi2 tissue factor pathway inhibitor 2 protein_coding Danio_rerio
ENSMUSG00000029664 Tfpi2 tissue factor pathway inhibitor 2 protein_coding Mus_musculus

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