C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nicotinamide phosphoribosyltransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105835 NAMPT 9606 - 7:106248285-106286326 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222553 NAMPT-001 106248285-106285192 protein_coding
  ENST00000354289 NAMPT-002 106261501-106284921 protein_coding
  ENST00000393618 NAMPT-011 106270215-106284951 processed_transcript
  ENST00000417537 NAMPT-004 106277056-106285612 protein_coding
  ENST00000424768 NAMPT-003 106275000-106286326 protein_coding
  ENST00000441045 NAMPT-012 106270258-106284951 processed_transcript
  ENST00000463871 NAMPT-009 106251125-106253618 retained_intron
  ENST00000467730 NAMPT-008 106268335-106269205 processed_transcript
  ENST00000484527 NAMPT-005 106269155-106284632 processed_transcript
  ENST00000486949 NAMPT-007 106271865-106284887 retained_intron
  ENST00000489358 NAMPT-010 106272039-106284950 processed_transcript
  ENST00000489732 NAMPT-006 106275327-106284950 retained_intron
  ENST00000491027 NAMPT-013 106263158-106284951 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000222553ENST00000354289ENST00000463871ENST00000467730ENST00000489732ENST00000491027
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000222553 37.374±0.00 19.991±0.00 1.464±0.00 8.107±4.06 7.362±0.00 12.404±6.11 10.573±5.76 9.550±5.81 21.031±10.87 50.564±0.00 6.837±4.99 8.473±2.31 8.457±0.89 4.999±2.33
ENST00000354289 N/A N/A N/A N/A N/A N/A 5.523±0.00 19.608±0.00 N/A N/A 2.028±0.00 20.705±0.00 7.636±2.38 N/A
ENST00000463871 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 31.737±0.00 N/A 7.980±0.00
ENST00000467730 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 62.573±0.00 N/A N/A
ENST00000489732 N/A N/A 1.467±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000491027 N/A N/A N/A 5.154±0.00 N/A 9.217±0.00 N/A N/A N/A N/A 3.900±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004514 IEA nicotinate-nucleotide diphosphorylase (carboxylating) activity
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0006769 TAS nicotinamide metabolic process
GO:0007165 TAS signal transduction
GO:0007267 TAS cell-cell signaling
GO:0007565 IEA female pregnancy
GO:0007623 IEA circadian rhythm
GO:0008144 IEA drug binding
GO:0008284 TAS positive regulation of cell proliferation
GO:0009435 IEA NAD biosynthetic process
GO:0014070 IEA response to organic cyclic compound
GO:0019674 TAS NAD metabolic process
GO:0032922 ISS circadian regulation of gene expression
GO:0042803 IEA protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0047280 IEA nicotinamide phosphoribosyltransferase activity
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0051770 IDA positive regulation of nitric-oxide synthase biosynthetic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030598 nampta nicotinamide phosphoribosyltransferase a protein_coding Danio_rerio
ENSDARG00000076694 NAMPT (2 of 6) nicotinamide phosphoribosyltransferase protein_coding Danio_rerio
ENSDARG00000078738 NAMPT (3 of 6) nicotinamide phosphoribosyltransferase protein_coding Danio_rerio
ENSDARG00000086096 NAMPT (4 of 6) nicotinamide phosphoribosyltransferase protein_coding Danio_rerio
ENSDARG00000087898 NAMPT (5 of 6) nicotinamide phosphoribosyltransferase protein_coding Danio_rerio
ENSDARG00000090151 NAMPT (6 of 6) nicotinamide phosphoribosyltransferase protein_coding Danio_rerio
ENSMUSG00000020572 Nampt nicotinamide phosphoribosyltransferase protein_coding Mus_musculus

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