C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105953 OGDH 9606 + 7:44606572-44709066 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222673 OGDH-001 44606639-44709066 protein_coding
  ENST00000419661 OGDH-008 44606595-44666851 protein_coding
  ENST00000439616 OGDH-005 44606572-44708230 protein_coding
  ENST00000443864 OGDH-007 44606588-44676594 protein_coding
  ENST00000444676 OGDH-006 44606628-44708138 protein_coding
  ENST00000447398 OGDH-003 44606591-44708278 protein_coding
  ENST00000449767 OGDH-002 44606591-44708328 protein_coding
  ENST00000459672 OGDH-009 44666621-44675245 processed_transcript
  ENST00000497326 OGDH-010 44666795-44674752 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000222673ENST00000419661ENST00000439616ENST00000444676ENST00000447398ENST00000449767
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000222673 22.111±0.00 18.721±0.00 7.787±0.00 11.078±5.77 19.809±16.49 12.813±5.98 65.806±51.13 24.602±20.54 8.604±0.50 17.707±14.20 74.368±47.31 23.988±8.41 25.645±6.92 23.858±0.77
ENST00000419661 N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.018±0.00 N/A N/A N/A N/A
ENST00000439616 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 24.688±0.00 N/A N/A N/A
ENST00000444676 N/A N/A 3.257±0.00 2.184±0.00 2.859±0.00 N/A 23.173±9.53 3.443±0.00 3.957±0.00 4.506±0.00 13.520±0.00 N/A N/A N/A
ENST00000447398 N/A N/A N/A 1.244±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000449767 4.435±0.00 N/A 4.674±0.00 11.546±0.00 8.406±0.00 3.356±0.00 N/A N/A N/A N/A N/A 4.348±0.00 N/A 6.442±0.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000J7 CIL_0000J7_0001 CGP 7:44577894-44709066
CIL_0000J8 CIL_0000J8_0001 CGP 7:44606572-44769881

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004591 IEA:ISS oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006091 ISS generation of precursor metabolites and energy
GO:0006096 IEA glycolytic process
GO:0006099 TAS:IEA tricarboxylic acid cycle
GO:0006103 IEA 2-oxoglutarate metabolic process
GO:0006104 IEA succinyl-CoA metabolic process
GO:0006554 TAS lysine catabolic process
GO:0006734 IEA NADH metabolic process
GO:0008152 IEA metabolic process
GO:0016624 IEA oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0021695 IEA cerebellar cortex development
GO:0021756 IEA striatum development
GO:0021766 IEA hippocampus development
GO:0021794 IEA thalamus development
GO:0021860 IEA pyramidal neuron development
GO:0022028 IEA tangential migration from the subventricular zone to the olfactory bulb
GO:0030976 IEA thiamine pyrophosphate binding
GO:0031072 IEA heat shock protein binding
GO:0031966 ISS mitochondrial membrane
GO:0034602 IEA oxoglutarate dehydrogenase (NAD+) activity
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045252 IEA oxoglutarate dehydrogenase complex
GO:0046872 IEA metal ion binding
GO:0051087 IEA chaperone binding
GO:0055114 IEA oxidation-reduction process
GO:0061034 IEA olfactory bulb mitral cell layer development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034270 ogdha oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide) protein_coding Danio_rerio
ENSDARG00000073805 ogdhb oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide) protein_coding Danio_rerio
ENSMUSG00000020456 Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) protein_coding Mus_musculus

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