C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ArfGAP with dual PH domains 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105963 ADAP1 9606 - 7:897901-955407 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265846 ADAP1-001 897903-954697 protein_coding
  ENST00000435943 ADAP1-005 904247-955406 protein_coding
  ENST00000437486 ADAP1-012 899465-920889 protein_coding
  ENST00000446141 ADAP1-002 897909-927216 protein_coding
  ENST00000449296 ADAP1-201 897901-927216 protein_coding
  ENST00000453175 ADAP1-014 898917-905077 protein_coding
  ENST00000453823 ADAP1-009 900533-927514 protein_coding
  ENST00000454383 ADAP1-008 900142-935180 protein_coding
  ENST00000463358 ADAP1-007 904152-945816 processed_transcript
  ENST00000477906 ADAP1-006 904187-955350 processed_transcript
  ENST00000478000 ADAP1-003 897910-905616 retained_intron
  ENST00000481406 ADAP1-013 903957-905138 retained_intron
  ENST00000488527 ADAP1-011 904247-923338 processed_transcript
  ENST00000495686 ADAP1-010 919968-927055 retained_intron
  ENST00000495809 ADAP1-004 897945-901399 retained_intron
  ENST00000539900 ADAP1-202 897901-955407 protein_coding
  ENST00000611167 ADAP1-203 897901-945816 protein_coding
  ENST00000617043 ADAP1-204 897901-920889 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000265846ENST00000435943ENST00000437486ENST00000446141ENST00000453175ENST00000453823ENST00000454383ENST00000463358ENST00000478000ENST00000495809ENST00000611167ENST00000617043
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000265846 1.258±0.00 N/A N/A 25.408±22.64 N/A 9.498±0.00 2.580±0.00 8.410±0.00 N/A 0.194±0.00 N/A 2.161±0.00 N/A
ENST00000435943 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.150±0.00 N/A N/A N/A
ENST00000437486 N/A N/A N/A 6.027±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000446141 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.375±0.00 N/A
ENST00000453175 N/A N/A N/A N/A N/A N/A N/A N/A 1.028±0.00 N/A N/A N/A N/A
ENST00000453823 N/A N/A N/A 33.001±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000454383 N/A N/A N/A N/A N/A N/A 0.952±0.00 N/A N/A N/A N/A N/A N/A
ENST00000463358 N/A N/A N/A 10.792±0.00 N/A 8.031±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000478000 1.606±0.00 2.789±0.00 1.369±0.00 4.701±0.00 3.717±0.00 2.458±0.00 N/A N/A N/A N/A 3.387±0.00 N/A 2.111±0.00
ENST00000495809 N/A N/A N/A N/A N/A N/A N/A 0.226±0.00 N/A N/A N/A N/A N/A
ENST00000611167 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.969±0.00 3.315±0.00 3.208±1.68 N/A
ENST00000617043 N/A N/A N/A N/A 1.050±0.00 N/A 0.139±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000186 CIL_000186_0001 CGP 7:876552-955407
CIL_000185 CIL_000185_0001 CGP 7:897901-975599

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005547 IEA phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007166 TAS cell surface receptor signaling pathway
GO:0008060 IDA:IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0032312 IEA regulation of ARF GTPase activity
GO:0043087 IMP regulation of GTPase activity
GO:0043533 TAS inositol 1,3,4,5 tetrakisphosphate binding
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086306 CABZ01073174.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000056413 Adap1 ArfGAP with dual PH domains 1 protein_coding Mus_musculus

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