C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FK506 binding protein 14, 22 kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106080 FKBP14 9606 - 7:30010587-30026684 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222803 FKBP14-001 30010587-30026684 protein_coding
  ENST00000412494 FKBP14-004 30014671-30026419 nonsense_mediated_decay
  ENST00000419018 FKBP14-002 30014288-30026662 nonsense_mediated_decay
  ENST00000479939 FKBP14-003 30022391-30026636 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000222803ENST00000412494ENST00000419018ENST00000479939
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000222803 1.426±0.00 1.513±0.00 0.257±0.00 0.494±0.10 2.098±0.25 0.876±0.09 1.062±0.45 1.208±0.90 0.695±0.61 1.099±0.52 0.283±0.23 2.314±0.29 2.269±0.22 1.456±0.63
ENST00000412494 N/A N/A 0.519±0.00 1.120±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000419018 0.971±0.00 N/A 0.267±0.00 N/A N/A N/A 0.576±0.00 0.617±0.00 N/A N/A N/A 2.731±0.00 N/A 1.904±0.00
ENST00000479939 N/A N/A 0.702±0.00 0.686±0.00 N/A N/A N/A N/A N/A 1.471±0.00 0.374±0.00 5.136±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003ZB CIL_0003ZB_0001 CGP 7:29920103-30026684
CIL_0003ZA CIL_0003ZA_0001 CGP 7:30010587-30130483

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000413 IBA protein peptidyl-prolyl isomerization
GO:0003755 IBA peptidyl-prolyl cis-trans isomerase activity
GO:0005509 IEA calcium ion binding
GO:0005528 IBA FK506 binding
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005789 IBA endoplasmic reticulum membrane
GO:0006457 IEA protein folding
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0044267 TAS cellular protein metabolic process
GO:0061077 IBA chaperone-mediated protein folding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040695 fkbp14 FK506 binding protein 14 protein_coding Danio_rerio
ENSMUSG00000038074 Fkbp14 FK506 binding protein 14 protein_coding Mus_musculus

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