C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 3, subfamily A, polypeptide 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106258 CYP3A5 9606 - 7:99648194-99679998 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222982 CYP3A5-001 99648194-99679996 protein_coding
  ENST00000339843 CYP3A5-201 99648200-99679998 protein_coding
  ENST00000439761 CYP3A5-003 99671222-99679996 protein_coding
  ENST00000456417 CYP3A5-011 99672661-99679993 nonsense_mediated_decay
  ENST00000461920 CYP3A5-008 99648198-99679988 retained_intron
  ENST00000463364 CYP3A5-009 99660219-99679966 retained_intron
  ENST00000463907 CYP3A5-004 99670910-99679996 retained_intron
  ENST00000466061 CYP3A5-006 99663542-99679996 retained_intron
  ENST00000469622 CYP3A5-012 99672589-99679993 retained_intron
  ENST00000469887 CYP3A5-002 99648198-99676576 retained_intron
  ENST00000473347 CYP3A5-010 99658833-99663582 retained_intron
  ENST00000480723 CYP3A5-013 99666716-99679953 processed_transcript
  ENST00000481825 CYP3A5-005 99660228-99679996 retained_intron
  ENST00000488187 CYP3A5-014 99652291-99660602 retained_intron
  ENST00000489231 CYP3A5-007 99674226-99679993 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000222982ENST00000439761ENST00000463364ENST00000463907ENST00000466061ENST00000469622ENST00000469887ENST00000473347ENST00000480723ENST00000481825ENST00000489231
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000222982 1.026±0.00 N/A N/A N/A 0.400±0.00 4.946±3.77 3.957±0.00 29.869±0.00 4.486±0.00 N/A 2.682±1.25 1.641±0.45 N/A
ENST00000439761 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.087±0.00 N/A 0.184±0.00 N/A
ENST00000463364 N/A N/A N/A N/A 3.131±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000463907 N/A 0.205±0.00 N/A N/A N/A N/A 29.815±0.00 N/A N/A N/A N/A N/A N/A
ENST00000466061 N/A N/A N/A N/A N/A N/A N/A 1.468±0.00 N/A N/A 4.136±0.00 0.038±0.00 N/A
ENST00000469622 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.950±0.00 N/A
ENST00000469887 N/A N/A 1.273±0.00 N/A N/A N/A 10.899±0.00 N/A 1.963±0.00 N/A 1.210±0.00 N/A N/A
ENST00000473347 1.954±0.00 N/A N/A 0.993±0.00 0.776±0.00 1.590±0.00 7.749±4.63 21.192±0.00 1.378±0.00 0.157±0.00 3.913±0.00 0.038±0.00 0.359±0.00
ENST00000480723 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.199±0.00 N/A
ENST00000481825 N/A N/A N/A N/A 2.351±0.00 N/A 17.082±0.00 N/A N/A N/A 1.304±0.00 N/A N/A
ENST00000489231 N/A N/A N/A N/A N/A N/A 59.652±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004TG CIL_0004TG_0001 CGP 7:99616946-99679998
CIL_0005LC CIL_0005LC_0004 CGP 7:99648194-99735196

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 ISS monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006805 TAS xenobiotic metabolic process
GO:0008202 TAS steroid metabolic process
GO:0009822 IDA alkaloid catabolic process
GO:0016491 IDA oxidoreductase activity
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0019825 TAS oxygen binding
GO:0020037 IEA heme binding
GO:0042737 IDA drug catabolic process
GO:0043231 TAS intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070330 IEA aromatase activity
GO:0070989 IDA oxidative demethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015575 cyp3c1 cytochrome P450, family 3, subfamily c, polypeptide 1 protein_coding Danio_rerio
ENSDARG00000037873 cyp3c1l2 cytochrome P450, family 3, subfamily c, polypeptide 1 like, 2 protein_coding Danio_rerio
ENSDARG00000037874 si:dkey-21n8.3 si:dkey-21n8.3 protein_coding Danio_rerio
ENSDARG00000045627 cyp3a65 cytochrome P450, family 3, subfamily A, polypeptide 65 protein_coding Danio_rerio
ENSDARG00000070021 cyp3c4 cytochrome P450, family 3, subfamily C, polypeptide 4 protein_coding Danio_rerio
ENSMUSG00000029630 Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25 protein_coding Mus_musculus
ENSMUSG00000029727 Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 protein_coding Mus_musculus
ENSMUSG00000038656 Cyp3a16 cytochrome P450, family 3, subfamily a, polypeptide 16 protein_coding Mus_musculus
ENSMUSG00000054417 Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44 protein_coding Mus_musculus
ENSMUSG00000056035 Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 protein_coding Mus_musculus
ENSMUSG00000061292 Cyp3a59 cytochrome P450, family 3, subfamily a, polypeptide 59 protein_coding Mus_musculus
ENSMUSG00000070419 Cyp3a57 cytochrome P450, family 3, subfamily a, polypeptide 57 protein_coding Mus_musculus
ENSMUSG00000075551 Cyp3a41a cytochrome P450, family 3, subfamily a, polypeptide 41A protein_coding Mus_musculus
ENSMUSG00000075552 Cyp3a41b cytochrome P450, family 3, subfamily a, polypeptide 41B protein_coding Mus_musculus

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