C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) subunit, alpha type, 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106588 PSMA2 9606 - 7:42916857-42932223 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000223321 PSMA2-001 42916857-42932223 protein_coding
  ENST00000411875 PSMA2-002 42918074-42932172 nonsense_mediated_decay
  ENST00000436986 PSMA2-005 42916882-42932154 nonsense_mediated_decay
  ENST00000445517 PSMA2-006 42917413-42932185 protein_coding
  ENST00000457444 PSMA2-007 42917309-42927464 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000223321ENST00000445517
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000223321 7.469±0.00 14.820±0.00 2.305±0.00 10.008±4.47 11.086±5.22 9.410±4.25 7.126±3.80 15.034±1.10 12.185±7.24 9.586±6.42 16.056±9.37 17.656±6.96 18.568±1.73 13.395±1.70
ENST00000445517 22.312±0.00 40.382±0.00 N/A 24.827±0.00 58.571±0.00 36.123±0.00 28.917±0.00 48.141±0.00 53.834±0.00 43.159±0.00 55.775±0.00 28.457±4.37 17.657±1.39 30.713±13.69

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0000932 ISS cytoplasmic mRNA processing body
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004175 IEA endopeptidase activity
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005839 ISS:IEA proteasome core complex
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0009615 IEP response to virus
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019773 IEA proteasome core complex, alpha-subunit complex
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035679 si:rp71-45k5.4 si:rp71-45k5.4 protein_coding Danio_rerio
ENSDARG00000040121 psma2 proteasome (prosome, macropain) subunit, alpha type, 2 protein_coding Danio_rerio

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