C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3-domain GRB2-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107295 SH3GL2 9606 + 9:17579082-17797129 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380607 SH3GL2-001 17579123-17797129 protein_coding
  ENST00000467085 SH3GL2-002 17579082-17630429 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000380607
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000380607 0.040±0.00 1.470±0.00 51.864±16.02 0.198±0.08 0.195±0.09 1.390±0.95 5.186±0.00 0.009±0.00 0.637±0.06 0.352±0.34 0.162±0.08 3.852±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008E9 CIL_0008E9_0001 VISTA 9:17022202-17624373
CIL_0007VQ CIL_0007VQ_0001 VISTA 9:17031973-17632582
CIL_00013X CIL_00013X_0001 CGP 9:17134982-17797129
CIL_00013Y CIL_00013Y_0001 CGP 9:17579082-18910950

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0002090 IEA regulation of receptor internalization
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006892 TAS post-Golgi vesicle-mediated transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007411 TAS axon guidance
GO:0007417 TAS central nervous system development
GO:0008289 IEA lipid binding
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0042802 IPI identical protein binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048488 IEA synaptic vesicle endocytosis
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023600 sh3gl2 SH3-domain GRB2-like 2 protein_coding Danio_rerio
ENSDARG00000039901 SH3GL2 (2 of 2) SH3-domain GRB2-like 2 protein_coding Danio_rerio
ENSMUSG00000028488 Sh3gl2 SH3-domain GRB2-like 2 protein_coding Mus_musculus

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