C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: unc-5 homolog B (C. elegans)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107731 UNC5B 9606 + 10:71212570-71302864 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335350 UNC5B-002 71212570-71302864 protein_coding
  ENST00000373192 UNC5B-001 71212927-71302864 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000335350ENST00000373192
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000335350 N/A 1.543±0.00 N/A 1.637±0.68 0.242±0.00 0.748±0.00 2.542±0.00 0.533±0.00 0.508±0.07 0.454±0.02 0.378±0.00 1.903±1.07 2.004±0.68 1.907±0.00
ENST00000373192 5.556±0.00 4.416±0.00 0.313±0.00 7.954±0.00 1.327±0.00 0.982±0.24 N/A 2.002±1.70 N/A 1.216±0.83 0.121±0.01 2.068±2.08 2.103±0.79 3.685±0.35

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0006915 TAS apoptotic process
GO:0007165 IEA signal transduction
GO:0007411 TAS axon guidance
GO:0014068 IMP positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016021 IEA integral component of membrane
GO:0033564 IEA anterior/posterior axon guidance
GO:0042981 TAS regulation of apoptotic process
GO:0043065 TAS positive regulation of apoptotic process
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:2001240 IMP negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033327 unc5b unc-5 homolog B (C. elegans) protein_coding Danio_rerio
ENSMUSG00000020099 Unc5b unc-5 homolog B (C. elegans) protein_coding Mus_musculus

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