C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: suppressor of fused homolog (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107882 SUFU 9606 + 10:102503987-102633535 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000369899 SUFU-004 102504007-102619462 protein_coding
  ENST00000369902 SUFU-001 102503987-102633535 protein_coding
  ENST00000423559 SUFU-006 102504079-102618659 protein_coding
  ENST00000471000 SUFU-007 102590809-102599543 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000369902ENST00000423559ENST00000471000
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000369902 3.764±0.00 3.266±0.00 N/A 2.014±0.00 2.615±1.62 1.812±1.56 2.238±0.00 2.943±2.15 1.505±0.54 1.638±1.38 3.394±2.70 4.715±2.80 7.868±2.26 8.872±0.72
ENST00000423559 N/A N/A 0.274±0.00 N/A N/A 0.324±0.00 N/A N/A N/A N/A 0.190±0.00 N/A N/A N/A
ENST00000471000 N/A N/A N/A N/A N/A N/A 0.565±0.00 N/A N/A 1.466±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MQ CIL_0008MQ_0001 VISTA 10:102469546-103070739
CIL_0005WM CIL_0005WM_0001 CGP 10:102479229-102633535
CIL_00065X CIL_00065X_0001 CGP 10:102503987-102658407

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001501 TAS skeletal system development
GO:0001843 IEA neural tube closure
GO:0001947 IEA heart looping
GO:0003714 TAS transcription corepressor activity
GO:0004871 TAS signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005929 IEA cilium
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006508 TAS proteolysis
GO:0007165 TAS signal transduction
GO:0007275 TAS multicellular organismal development
GO:0007368 IEA determination of left/right symmetry
GO:0008013 IEA beta-catenin binding
GO:0008134 IDA transcription factor binding
GO:0019901 IPI protein kinase binding
GO:0021513 IEA spinal cord dorsal/ventral patterning
GO:0021775 IEA smoothened signaling pathway involved in ventral spinal cord interneuron specification
GO:0021776 IEA smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
GO:0042992 TAS negative regulation of transcription factor import into nucleus
GO:0042994 IEA cytoplasmic sequestering of transcription factor
GO:0043433 TAS negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043588 IEA skin development
GO:0045668 TAS negative regulation of osteoblast differentiation
GO:0045879 TAS negative regulation of smoothened signaling pathway
GO:0072372 IEA primary cilium
GO:1901621 IEA negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:2000059 IEA negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000025231 Sufu suppressor of fused homolog (Drosophila) protein_coding Mus_musculus

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