C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutaredoxin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108010 GLRX3 9606 + 10:130136399-130184521 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331244 GLRX3-001 130136399-130179664 protein_coding
  ENST00000368644 GLRX3-002 130136399-130182881 protein_coding
  ENST00000481034 GLRX3-003 130136399-130184521 nonsense_mediated_decay
  ENST00000486974 GLRX3-005 130159746-130160873 processed_transcript
  ENST00000496195 GLRX3-004 130179374-130180382 processed_transcript
  ENST00000619341 GLRX3-006 130180185-130183643 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000331244ENST00000368644ENST00000481034
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000331244 12.970±0.00 13.402±0.00 1.209±0.00 6.149±2.62 10.113±0.00 10.809±0.00 8.941±8.26 18.670±0.00 13.112±0.00 5.605±4.34 4.603±3.69 27.239±21.92 26.069±5.92 46.833±2.93
ENST00000368644 N/A 1.502±0.00 0.174±0.00 0.487±0.17 0.915±0.10 0.257±0.00 0.220±0.00 0.734±0.44 N/A 0.889±0.00 0.250±0.00 1.175±0.45 N/A N/A
ENST00000481034 N/A N/A N/A N/A N/A N/A 0.175±0.00 N/A N/A 0.376±0.00 N/A 6.300±4.91 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007OP CIL_0007OP_0001 UCNEbase 10:128166009-130159815
CIL_0007UL CIL_0007UL_0001 VISTA 10:129592822-130194584
CIL_0001LF CIL_0001LF_0001 CGP 10:130136399-131311721

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002026 ISS regulation of the force of heart contraction
GO:0005080 IEA protein kinase C binding
GO:0005515 IPI protein binding
GO:0005681 IEA spliceosomal complex
GO:0007067 IEA mitotic nuclear division
GO:0009055 IEA electron carrier activity
GO:0010614 ISS negative regulation of cardiac muscle hypertrophy
GO:0015035 IEA protein disulfide oxidoreductase activity
GO:0030018 IEA Z disc
GO:0044822 IDA poly(A) RNA binding
GO:0045454 IEA cell redox homeostasis
GO:0046872 IEA metal ion binding
GO:0051536 IEA iron-sulfur cluster binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031439 glrx3 glutaredoxin 3 protein_coding Danio_rerio
ENSMUSG00000031068 Glrx3 glutaredoxin 3 protein_coding Mus_musculus

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