C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hydroxysteroid (17-beta) dehydrogenase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108786 HSD17B1 9606 + 17:42549214-42555213 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000225929 HSD17B1-002 42552934-42555213 protein_coding
  ENST00000585807 HSD17B1-001 42549214-42555213 protein_coding
  ENST00000587280 HSD17B1-004 42552923-42554051 retained_intron
  ENST00000590299 HSD17B1-005 42552923-42555093 nonsense_mediated_decay
  ENST00000593215 HSD17B1-003 42552922-42554238 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000225929ENST00000585807
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000225929 N/A N/A N/A N/A 6.750±0.00 N/A N/A N/A N/A N/A N/A 7.068±0.00 205.010±118.29 N/A
ENST00000585807 0.789±0.00 0.927±0.00 0.246±0.00 0.678±0.15 1.081±0.00 0.744±0.29 0.494±0.00 0.403±0.31 0.197±0.00 0.400±0.10 0.215±0.00 0.899±0.53 2.903±0.00 0.656±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000467 CIL_000467_0001 CGP 17:42536172-42555213
CIL_000463 CIL_000463_0001 CGP 17:42549214-42566277

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 TAS catalytic activity
GO:0004303 IEA estradiol 17-beta-dehydrogenase activity
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006694 TAS steroid biosynthetic process
GO:0006703 IEA estrogen biosynthetic process
GO:0008152 IEA metabolic process
GO:0008202 TAS steroid metabolic process
GO:0008210 TAS estrogen metabolic process
GO:0016491 IEA oxidoreductase activity
GO:0031965 IDA nuclear membrane
GO:0044281 TAS small molecule metabolic process
GO:0047035 IEA testosterone dehydrogenase (NAD+) activity
GO:0055114 IEA oxidation-reduction process
GO:0060348 IEA bone development
GO:0061370 IEA testosterone biosynthetic process
GO:0071248 IEA cellular response to metal ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027469 hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 protein_coding Danio_rerio
ENSMUSG00000019301 Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 protein_coding Mus_musculus

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