C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109339 MAPK10 9606 - 4:86015123-86594131 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310816 MAPK10-003 86016478-86453145 nonsense_mediated_decay
  ENST00000359221 MAPK10-012 86016478-86360063 protein_coding
  ENST00000361569 MAPK10-005 86016479-86453130 protein_coding
  ENST00000395157 MAPK10-014 86016478-86107330 protein_coding
  ENST00000395160 MAPK10-004 86016480-86107653 protein_coding
  ENST00000395161 MAPK10-201 86015123-86360222 protein_coding
  ENST00000395166 MAPK10-002 86016480-86358870 protein_coding
  ENST00000395169 MAPK10-001 86015123-86360116 protein_coding
  ENST00000430389 MAPK10-033 86102909-86107272 retained_intron
  ENST00000449047 MAPK10-202 86016480-86370890 protein_coding
  ENST00000468020 MAPK10-010 86095426-86101214 processed_transcript
  ENST00000472236 MAPK10-009 86095135-86101922 processed_transcript
  ENST00000475679 MAPK10-007 86106807-86117766 retained_intron
  ENST00000479377 MAPK10-008 86099164-86103244 processed_transcript
  ENST00000486985 MAPK10-006 86101122-86117779 processed_transcript
  ENST00000489368 MAPK10-011 86067824-86089549 processed_transcript
  ENST00000502302 MAPK10-018 86159320-86594110 protein_coding
  ENST00000503911 MAPK10-020 86159382-86453183 protein_coding
  ENST00000504397 MAPK10-031 86300580-86399806 processed_transcript
  ENST00000505356 MAPK10-032 86164446-86354644 processed_transcript
  ENST00000506385 MAPK10-024 86354528-86360024 processed_transcript
  ENST00000506773 MAPK10-026 86107315-86358374 protein_coding
  ENST00000508262 MAPK10-016 86016480-86099277 retained_intron
  ENST00000509464 MAPK10-030 86107254-86357704 protein_coding
  ENST00000511167 MAPK10-029 86107225-86357895 protein_coding
  ENST00000511328 MAPK10-021 86107237-86453180 protein_coding
  ENST00000512017 MAPK10-027 86103188-86358131 protein_coding
  ENST00000512046 MAPK10-019 86354568-86594119 processed_transcript
  ENST00000512564 MAPK10-028 86107223-86358130 protein_coding
  ENST00000512689 MAPK10-025 86107320-86358512 protein_coding
  ENST00000513186 MAPK10-017 86159388-86594131 protein_coding
  ENST00000513839 MAPK10-013 86101942-86594110 processed_transcript
  ENST00000514856 MAPK10-022 86354530-86360224 processed_transcript
  ENST00000515400 MAPK10-015 86017034-86107325 protein_coding
  ENST00000515650 MAPK10-023 86356867-86360076 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310816ENST00000359221ENST00000361569ENST00000395157ENST00000395160ENST00000395161ENST00000395169ENST00000449047ENST00000479377ENST00000508262ENST00000515400
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310816 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.431±0.00 N/A N/A
ENST00000359221 N/A N/A N/A 17.603±5.32 N/A N/A 0.144±0.06 N/A N/A N/A N/A N/A 0.280±0.00 2.448±0.00
ENST00000361569 0.979±0.00 N/A 1.077±0.00 19.035±0.00 6.541±0.00 0.862±0.00 0.226±0.00 2.291±0.00 3.196±0.00 1.776±0.00 N/A 2.620±0.51 0.169±0.00 2.754±0.00
ENST00000395157 0.928±0.00 1.043±0.00 2.220±0.00 N/A 2.318±1.38 2.171±0.00 0.220±0.00 2.722±0.00 0.123±0.00 1.555±0.17 N/A 1.867±1.44 0.262±0.02 4.853±0.11
ENST00000395160 N/A N/A N/A N/A 0.536±0.00 0.816±0.00 N/A N/A N/A N/A N/A 0.960±0.00 N/A N/A
ENST00000395161 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.006±0.00 N/A N/A N/A
ENST00000395169 N/A N/A N/A 16.250±3.79 0.495±0.00 0.380±0.00 N/A 0.334±0.26 0.018±0.00 0.510±0.00 0.002±0.00 1.772±0.00 N/A 2.471±0.00
ENST00000449047 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.158±0.00 N/A
ENST00000479377 N/A N/A N/A N/A N/A N/A N/A 2.249±0.00 N/A N/A N/A N/A N/A N/A
ENST00000508262 N/A N/A N/A N/A N/A N/A 0.443±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000515400 1.468±0.00 1.214±0.00 N/A N/A N/A N/A 0.251±0.00 N/A N/A 1.284±0.00 0.021±0.00 1.035±0.34 0.308±0.05 5.701±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000530 CIL_000530_0002 CGP 4:85475114-86594131
CIL_00052Z CIL_00052Z_0002 CGP 4:86015123-86815171

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000187 TAS activation of MAPK activity
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004672 IEA protein kinase activity
GO:0004705 ISS JUN kinase activity
GO:0004707 IEA MAP kinase activity
GO:0004708 TAS MAP kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0005739 ISS mitochondrion
GO:0005829 TAS cytosol
GO:0005886 ISS plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007254 ISS JNK cascade
GO:0007258 ISS JUN phosphorylation
GO:0008152 IEA metabolic process
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0045087 TAS innate immune response
GO:0051090 TAS regulation of sequence-specific DNA binding transcription factor activity
GO:0051403 TAS stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025747 mapk10 mitogen-activated protein kinase 10 protein_coding Danio_rerio
ENSMUSG00000046709 Mapk10 mitogen-activated protein kinase 10 protein_coding Mus_musculus

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