C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kelch-like family member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109466 KLHL2 9606 + 4:165207618-165323156 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000226725 KLHL2-001 165207618-165323153 protein_coding
  ENST00000421009 KLHL2-004 165220001-165322945 protein_coding
  ENST00000506541 KLHL2-009 165238776-165310752 processed_transcript
  ENST00000506761 KLHL2-005 165240348-165322711 protein_coding
  ENST00000506824 KLHL2-003 165210036-165323153 nonsense_mediated_decay
  ENST00000509028 KLHL2-006 165263257-165322538 processed_transcript
  ENST00000509704 KLHL2-008 165209400-165263281 protein_coding
  ENST00000511305 KLHL2-007 165207823-165238831 protein_coding
  ENST00000514860 KLHL2-002 165209893-165322458 protein_coding
  ENST00000538127 KLHL2-201 165210019-165323156 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000226725ENST00000421009ENST00000506541ENST00000506761ENST00000506824ENST00000509028ENST00000509704ENST00000514860ENST00000538127
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000226725 3.462±0.00 1.123±0.00 0.503±0.00 8.243±0.00 0.858±0.55 0.981±0.36 1.899±0.00 4.617±0.00 4.178±0.00 2.674±1.72 0.202±0.00 1.273±0.38 1.125±0.26 2.182±1.24
ENST00000421009 N/A 0.937±0.00 N/A 5.517±0.79 0.774±0.00 N/A N/A 2.973±0.00 N/A N/A 0.242±0.00 N/A N/A 1.431±0.15
ENST00000506541 N/A N/A N/A 12.301±0.00 1.358±0.00 N/A N/A 4.843±0.00 N/A N/A 0.473±0.00 N/A N/A N/A
ENST00000506761 3.441±0.00 N/A 0.669±0.00 N/A N/A 1.855±0.70 0.183±0.00 1.047±0.00 1.496±0.06 1.240±0.00 N/A 1.393±0.54 1.397±0.00 2.626±0.00
ENST00000506824 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.696±0.00 0.546±0.11 0.980±0.00
ENST00000509028 N/A 4.089±0.00 N/A 9.274±4.26 1.556±0.10 N/A 1.421±0.00 N/A 2.617±0.76 2.570±0.39 N/A 1.260±0.29 1.524±0.97 2.351±0.36
ENST00000509704 N/A N/A N/A N/A N/A N/A N/A N/A 3.208±0.00 N/A N/A N/A N/A N/A
ENST00000514860 N/A N/A N/A N/A 0.786±0.00 0.784±0.00 N/A N/A N/A 2.664±0.00 N/A 0.674±0.00 N/A N/A
ENST00000538127 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.436±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IDA actin binding
GO:0005515 IPI:IEA protein binding
GO:0005737 ISS cytoplasm
GO:0015629 IDA actin cytoskeleton
GO:0016567 ISS protein ubiquitination
GO:0031463 ISS Cul3-RING ubiquitin ligase complex
GO:0042995 IEA cell projection

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061786 klhl2 kelch-like family member 2 protein_coding Danio_rerio
ENSMUSG00000031605 Klhl2 kelch-like 2, Mayven protein_coding Mus_musculus

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