C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NK3 homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109705 NKX3-2 9606 - 4:13540830-13545050 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000382438 NKX3-2-001 13540830-13545050 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000382438
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000382438 0.574±0.00 0.027±0.00 0.094±0.04 4.531±3.72 0.022±0.00 0.036±0.00 0.110±0.00 0.011±0.00 0.010±0.00 0.193±0.09 0.242±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00097J CIL_00097J_0001 VISTA 4:13215873-13817543
CIL_00026M CIL_00026M_0001 CGP 4:13361354-13545050
CIL_00026L CIL_00026L_0001 CGP 4:13540830-13627723

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001501 TAS skeletal system development
GO:0003677 IEA DNA binding
GO:0005634 IEA nucleus
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0007368 IEA determination of left/right symmetry
GO:0031016 IEA pancreas development
GO:0032331 ISS negative regulation of chondrocyte differentiation
GO:0042474 IEA middle ear morphogenesis
GO:0043066 IEA negative regulation of apoptotic process
GO:0048513 IEA organ development
GO:0048536 IEA spleen development
GO:0048645 IEA organ formation
GO:0048705 IEA skeletal system morphogenesis
GO:0048706 IEA embryonic skeletal system development
GO:0055123 IEA digestive system development
GO:0060576 IEA intestinal epithelial cell development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037639 nkx3.2 NK3 homeobox 2 protein_coding Danio_rerio
ENSMUSG00000049691 Nkx3-2 NK3 homeobox 2 protein_coding Mus_musculus

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