C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: crystallin, alpha B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109846 CRYAB 9606 - 11:111908565-111923722 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000227251 CRYAB-003 111908629-111912010 protein_coding
  ENST00000524660 CRYAB-012 111908619-111909267 protein_coding
  ENST00000525823 CRYAB-008 111908620-111910893 protein_coding
  ENST00000526167 CRYAB-010 111908771-111910830 protein_coding
  ENST00000526180 CRYAB-001 111908565-111912014 protein_coding
  ENST00000527899 CRYAB-005 111908768-111913347 protein_coding
  ENST00000527950 CRYAB-013 111908623-111923722 protein_coding
  ENST00000528628 CRYAB-007 111910419-111912927 protein_coding
  ENST00000528961 CRYAB-009 111908766-111910860 protein_coding
  ENST00000529647 CRYAB-014 111908903-111913579 protein_coding
  ENST00000531198 CRYAB-015 111908646-111913197 protein_coding
  ENST00000533280 CRYAB-011 111908620-111910744 protein_coding
  ENST00000533475 CRYAB-002 111908623-111913849 protein_coding
  ENST00000533879 CRYAB-006 111910445-111913213 protein_coding
  ENST00000533971 CRYAB-004 111909762-111911816 protein_coding
  ENST00000616970 CRYAB-201 111908622-111913213 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000227251ENST00000526180ENST00000527950ENST00000528628ENST00000528961ENST00000529647ENST00000533280ENST00000533879ENST00000533971ENST00000616970
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000227251 144.268±0.00 85.546±0.00 N/A 401.545±0.00 1067.810±0.00 248.767±0.00 849.442±622.80 986.849±0.00 N/A 132.699±0.00 775.487±0.00 N/A 96.435±0.00 63.326±0.00
ENST00000526180 N/A N/A 4.171±0.00 48.894±0.00 3.884±0.00 1.645±0.00 N/A N/A N/A N/A N/A 31.427±0.00 N/A N/A
ENST00000527950 42.730±0.00 N/A 5.981±0.00 62.707±0.00 N/A 2.709±0.00 N/A N/A 10.465±0.00 25.186±22.53 N/A 19.527±16.31 73.341±31.98 3.243±0.00
ENST00000528628 N/A N/A 16.790±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 1.414±0.00 N/A N/A
ENST00000528961 114.081±0.00 105.189±0.00 N/A 703.117±0.00 1225.410±0.00 297.688±0.00 1437.940±0.00 1578.660±0.00 N/A 138.440±0.00 635.338±0.00 N/A N/A 90.738±0.00
ENST00000529647 N/A N/A N/A N/A 7.044±0.00 N/A N/A N/A 10.341±0.00 N/A N/A 3.479±0.00 N/A 1.831±0.00
ENST00000533280 N/A N/A N/A 204.632±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000533879 N/A N/A N/A N/A N/A 4.914±0.00 N/A 4.196±0.00 N/A N/A N/A 3.669±0.00 N/A 3.672±0.00
ENST00000533971 N/A N/A 5.860±0.00 N/A 4.078±0.00 N/A N/A N/A 7.187±0.00 3.341±0.00 N/A 0.570±0.00 N/A N/A
ENST00000616970 42.428±0.00 42.624±0.00 N/A N/A N/A 40.238±37.00 N/A N/A N/A 3.332±0.00 N/A 32.989±37.59 N/A 48.467±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0002088 IEA lens development in camera-type eye
GO:0005212 IEA structural constituent of eye lens
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005794 IEA Golgi apparatus
GO:0005829 IEA cytosol
GO:0005886 IEA plasma membrane
GO:0006457 IEA protein folding
GO:0006936 TAS muscle contraction
GO:0007021 IEA tubulin complex assembly
GO:0007517 IEA muscle organ development
GO:0007568 IEA aging
GO:0008017 IEA microtubule binding
GO:0008092 IEA cytoskeletal protein binding
GO:0009986 IEA cell surface
GO:0010629 IEA negative regulation of gene expression
GO:0010941 IMP regulation of cell death
GO:0015630 IEA microtubule cytoskeleton
GO:0030018 IEA Z disc
GO:0030308 IEA negative regulation of cell growth
GO:0031109 IEA microtubule polymerization or depolymerization
GO:0031674 IEA I band
GO:0032355 IEA response to estradiol
GO:0032387 IDA negative regulation of intracellular transport
GO:0032432 IEA actin filament bundle
GO:0042542 IEA response to hydrogen peroxide
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0043010 IEA camera-type eye development
GO:0043066 IDA negative regulation of apoptotic process
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043292 IEA contractile fiber
GO:0046872 IEA metal ion binding
GO:0051082 IPI unfolded protein binding
GO:0051260 IDA protein homooligomerization
GO:0051403 IEA stress-activated MAPK cascade
GO:0060561 IEA apoptotic process involved in morphogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:0071480 IMP cellular response to gamma radiation
GO:2000378 IEA negative regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042621 cryaba crystallin, alpha B, a protein_coding Danio_rerio
ENSDARG00000052447 cryabb crystallin, alpha B, b protein_coding Danio_rerio
ENSMUSG00000032060 Cryab crystallin, alpha B protein_coding Mus_musculus

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