C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin D1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110092 CCND1 9606 + 11:69641087-69654474 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000227507 CCND1-001 69641087-69654474 protein_coding
  ENST00000535993 CCND1-003 69641231-69643317 retained_intron
  ENST00000536559 CCND1-004 69641206-69648240 protein_coding
  ENST00000539241 CCND1-002 69641165-69644188 retained_intron
  ENST00000542367 CCND1-006 69647957-69651407 retained_intron
  ENST00000545484 CCND1-005 69643712-69648143 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000227507ENST00000542367
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000227507 10.005±0.00 7.463±0.00 3.356±1.06 52.867±37.07 5.603±1.29 9.681±3.83 10.526±0.55 26.022±11.56 14.958±6.94 1.157±0.13 9.432±2.96 45.548±10.52 8.735±6.73
ENST00000542367 N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.185±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TF CIL_0007TF_0001 VISTA 11:69193417-69797766
CIL_0001SO CIL_0001SO_0002 CGP 11:69641087-69675416

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000079 IEA regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000278 TAS mitotic cell cycle
GO:0000307 IDA cyclin-dependent protein kinase holoenzyme complex
GO:0000320 IEA re-entry into mitotic cell cycle
GO:0001889 IEA liver development
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0003714 IDA transcription corepressor activity
GO:0004672 IEA protein kinase activity
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005923 IEA tight junction
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007049 IEA cell cycle
GO:0007219 TAS Notch signaling pathway
GO:0007595 IEA lactation
GO:0008134 IPI transcription factor binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0010033 IEA response to organic substance
GO:0010039 IEA response to iron ion
GO:0010165 IEA response to X-ray
GO:0010243 IEA response to organonitrogen compound
GO:0010971 IDA positive regulation of G2/M transition of mitotic cell cycle
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IEA membrane
GO:0016055 IEA Wnt signaling pathway
GO:0016301 IEA kinase activity
GO:0016538 IEA cyclin-dependent protein serine/threonine kinase regulator activity
GO:0017053 IDA transcriptional repressor complex
GO:0019899 IPI enzyme binding
GO:0019901 IPI:IEA protein kinase binding
GO:0030178 IEA negative regulation of Wnt signaling pathway
GO:0030857 IEA negative regulation of epithelial cell differentiation
GO:0030968 IEA endoplasmic reticulum unfolded protein response
GO:0031100 IEA organ regeneration
GO:0031571 IDA mitotic G1 DNA damage checkpoint
GO:0032026 IEA response to magnesium ion
GO:0032403 IEA protein complex binding
GO:0033197 IEA response to vitamin E
GO:0033327 IEA Leydig cell differentiation
GO:0033598 IEA mammary gland epithelial cell proliferation
GO:0033601 IEA positive regulation of mammary gland epithelial cell proliferation
GO:0042493 IEP response to drug
GO:0042826 IPI histone deacetylase binding
GO:0043627 IEA response to estrogen
GO:0045444 IEA fat cell differentiation
GO:0045471 IEA response to ethanol
GO:0045737 IDA positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0048545 IEA response to steroid hormone
GO:0051301 IEA cell division
GO:0051384 IEA response to glucocorticoid
GO:0051412 IEA response to corticosterone
GO:0051592 IEA response to calcium ion
GO:0051726 IEA regulation of cell cycle
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060749 IEA mammary gland alveolus development
GO:0070064 IDA proline-rich region binding
GO:0070141 IDA response to UV-A
GO:0071157 IDA negative regulation of cell cycle arrest
GO:0071310 IEA cellular response to organic substance
GO:2000045 IEA regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035750 ccnd1 cyclin D1 protein_coding Danio_rerio
ENSMUSG00000070348 Ccnd1 cyclin D1 protein_coding Mus_musculus

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