C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cholecystokinin B receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110148 CCKBR 9606 + 11:6259736-6272127 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000334619 CCKBR-001 6259736-6272127 protein_coding
  ENST00000525014 CCKBR-007 6259875-6270255 protein_coding
  ENST00000525462 CCKBR-003 6259926-6272127 protein_coding
  ENST00000531712 CCKBR-002 6259926-6269817 protein_coding
  ENST00000532396 CCKBR-006 6270776-6271214 processed_transcript
  ENST00000532715 CCKBR-004 6259806-6272062 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonKidneyLungOvaryPlacentaTestisENST00000334619ENST00000525014ENST00000532715
Transcript ID Adipose Brain Breast Colon Kidney Lung Ovary Placenta Testis
ENST00000334619 N/A 2.845±0.00 N/A N/A N/A N/A 0.757±0.49 N/A N/A
ENST00000525014 N/A N/A N/A N/A N/A N/A N/A 0.117±0.00 N/A
ENST00000532715 0.072±0.00 3.137±0.00 0.017±0.00 0.262±0.00 0.033±0.00 0.046±0.00 0.369±0.00 0.070±0.01 0.246±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004B5 CIL_0004B5_0001 CGP 11:6234765-6272127
CIL_00077J CIL_00077J_0001 CGP 11:6259736-6320647

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001696 IEA gastric acid secretion
GO:0004435 TAS phosphatidylinositol phospholipase C activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0004951 TAS cholecystokinin receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0007166 NAS cell surface receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007200 TAS phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IDA positive regulation of cytosolic calcium ion concentration
GO:0007586 TAS digestion
GO:0007600 TAS sensory perception
GO:0007631 TAS feeding behavior
GO:0008152 TAS metabolic process
GO:0008283 TAS cell proliferation
GO:0008284 IDA positive regulation of cell proliferation
GO:0015054 IDA gastrin receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0031741 IDA type B gastrin/cholecystokinin receptor binding
GO:0038188 TAS cholecystokinin signaling pathway
GO:0043551 TAS regulation of phosphatidylinositol 3-kinase activity
GO:0046935 TAS 1-phosphatidylinositol-3-kinase regulator activity
GO:0048565 IEA digestive tract development
GO:0048732 IEA gland development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074117 CCKBR (1 of 2) cholecystokinin B receptor protein_coding Danio_rerio
ENSDARG00000076824 CCKBR (2 of 2) cholecystokinin B receptor protein_coding Danio_rerio
ENSMUSG00000030898 Cckbr cholecystokinin B receptor protein_coding Mus_musculus

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