C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apolipoprotein A-IV
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110244 APOA4 9606 - 11:116820700-116823306 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357780 APOA4-001 116820700-116823306 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonHeartLiverLungOvaryPlacentaTestisENST00000357780
Transcript ID Adipose Brain Colon Heart Liver Lung Ovary Placenta Testis
ENST00000357780 0.032±0.00 0.043±0.00 0.194±0.01 0.034±0.02 62.581±62.45 0.040±0.00 0.070±0.03 0.044±0.00 0.033±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008EK CIL_0008EK_0001 VISTA 11:116351165-116951910
CIL_0007RC CIL_0007RC_0001 VISTA 11:116660805-117262910

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0002227 IDA innate immune response in mucosa
GO:0005319 TAS lipid transporter activity
GO:0005507 IDA copper ion binding
GO:0005576 NAS:IEA extracellular region
GO:0005615 IDA extracellular space
GO:0005769 TAS early endosome
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005829 TAS cytosol
GO:0006869 IDA:IEA lipid transport
GO:0006982 IDA response to lipid hydroperoxide
GO:0007159 IDA leukocyte cell-cell adhesion
GO:0007603 TAS phototransduction, visible light
GO:0008203 IDA cholesterol metabolic process
GO:0008289 IMP:IEA lipid binding
GO:0009986 IDA cell surface
GO:0010873 IDA positive regulation of cholesterol esterification
GO:0010898 IDA positive regulation of triglyceride catabolic process
GO:0016209 IDA antioxidant activity
GO:0017127 IDA cholesterol transporter activity
GO:0019430 IDA removal of superoxide radicals
GO:0030300 IEA regulation of intestinal cholesterol absorption
GO:0031210 IDA phosphatidylcholine binding
GO:0032374 IDA regulation of cholesterol transport
GO:0033344 IDA cholesterol efflux
GO:0033700 IDA phospholipid efflux
GO:0034361 IDA very-low-density lipoprotein particle
GO:0034364 IDA high-density lipoprotein particle
GO:0034371 IC chylomicron remodeling
GO:0034372 IDA very-low-density lipoprotein particle remodeling
GO:0034375 IC high-density lipoprotein particle remodeling
GO:0034378 TAS chylomicron assembly
GO:0034445 IDA negative regulation of plasma lipoprotein particle oxidation
GO:0035634 IEA response to stilbenoid
GO:0042157 TAS:IEA lipoprotein metabolic process
GO:0042627 IDA chylomicron
GO:0042632 IDA cholesterol homeostasis
GO:0042744 IDA hydrogen peroxide catabolic process
GO:0042803 IDA protein homodimerization activity
GO:0043691 IDA reverse cholesterol transport
GO:0044240 IDA multicellular organismal lipid catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045723 IDA positive regulation of fatty acid biosynthetic process
GO:0046470 IDA phosphatidylcholine metabolic process
GO:0051006 IDA positive regulation of lipoprotein lipase activity
GO:0055088 IDA lipid homeostasis
GO:0060228 IDA phosphatidylcholine-sterol O-acyltransferase activator activity
GO:0065005 IMP protein-lipid complex assembly
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020866 APOA4 (1 of 4) apolipoprotein A-IV protein_coding Danio_rerio
ENSDARG00000040298 apoa4 apolipoprotein A-IV protein_coding Danio_rerio
ENSDARG00000086281 APOA4 (3 of 4) apolipoprotein A-IV protein_coding Danio_rerio
ENSDARG00000094929 APOA4 (4 of 4) apolipoprotein A-IV protein_coding Danio_rerio
ENSMUSG00000032080 Apoa4 apolipoprotein A-IV protein_coding Mus_musculus

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