C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: matrix Gla protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111341 MGP 9606 - 12:14881181-14885926 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000228938 MGP-004 14881898-14885857 protein_coding
  ENST00000507170 MGP-002 14883054-14885854 retained_intron
  ENST00000539261 MGP-001 14881181-14885926 protein_coding
  ENST00000545199 MGP-003 14881891-14884245 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000228938ENST00000539261ENST00000545199
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000228938 201.441±0.00 241.948±0.00 N/A 35.494±0.00 466.851±0.00 857.565±0.00 N/A 160.556±0.00 7.308±0.00 752.391±0.00 56.952±0.00 128.125±0.00 30.107±15.85 19.765±0.00
ENST00000539261 N/A N/A 29.453±0.00 4.474±0.00 164.634±0.00 33.322±0.00 28.339±0.00 4.097±0.00 115.579±0.00 95.772±0.00 9.393±0.00 21.422±14.95 13.453±9.51 5.290±0.00
ENST00000545199 94.894±0.00 151.391±0.00 27.303±0.00 8.281±0.00 231.426±106.58 49.380±0.00 108.642±82.45 263.846±0.00 65.006±59.55 682.833±0.00 26.592±0.99 149.821±135.21 163.650±26.14 348.109±334.94

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036X CIL_00036X_0001 CGP 12:14784579-14906586
CIL_00036Y CIL_00036Y_0001 CGP 12:14803572-14906586
CIL_000370 CIL_000370_0001 CGP 12:14825569-14885926
CIL_000371 CIL_000371_0001 CGP 12:14881181-14939082

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001502 TAS cartilage condensation
GO:0001503 IEA ossification
GO:0005201 TAS extracellular matrix structural constituent
GO:0005509 IEA calcium ion binding
GO:0005576 IEA extracellular region
GO:0005578 TAS proteinaceous extracellular matrix
GO:0008147 TAS structural constituent of bone
GO:0030154 IEA cell differentiation
GO:0030500 IEA regulation of bone mineralization
GO:0031012 IDA extracellular matrix
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000030218 Mgp matrix Gla protein protein_coding Mus_musculus

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