C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAS protein activator like 1 (GAP1 like)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111344 RASAL1 9606 - 12:113098819-113136239 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261729 RASAL1-001 113099278-113136239 protein_coding
  ENST00000418411 RASAL1-002 113103040-113136239 processed_transcript
  ENST00000446861 RASAL1-004 113099508-113135750 protein_coding
  ENST00000546530 RASAL1-008 113098819-113136224 protein_coding
  ENST00000546727 RASAL1-005 113099892-113135504 retained_intron
  ENST00000547810 RASAL1-009 113115682-113135754 processed_transcript
  ENST00000548055 RASAL1-007 113099887-113135504 protein_coding
  ENST00000548972 RASAL1-003 113107216-113135750 processed_transcript
  ENST00000549444 RASAL1-010 113099512-113103099 processed_transcript
  ENST00000551051 RASAL1-006 113099888-113135738 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261729ENST00000446861ENST00000546530ENST00000546727ENST00000548055ENST00000548972ENST00000549444ENST00000551051
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261729 N/A N/A N/A 2.157±1.13 N/A N/A N/A N/A N/A N/A N/A 0.356±0.21 0.160±0.00 0.271±0.00
ENST00000446861 0.024±0.00 N/A N/A N/A 0.882±0.00 N/A N/A 2.216±0.00 N/A 0.134±0.00 N/A N/A N/A 0.188±0.00
ENST00000546530 0.038±0.00 N/A N/A 4.576±0.00 N/A N/A N/A 2.902±0.00 N/A N/A N/A 0.157±0.00 N/A N/A
ENST00000546727 N/A N/A N/A N/A N/A 0.087±0.00 N/A N/A N/A 0.074±0.00 N/A N/A N/A 0.121±0.00
ENST00000548055 N/A N/A 2.372±0.00 3.164±0.00 N/A 0.445±0.27 N/A N/A N/A N/A N/A 0.970±0.92 0.189±0.06 0.123±0.00
ENST00000548972 0.030±0.00 N/A N/A N/A N/A N/A 0.047±0.00 0.342±0.00 0.080±0.00 0.305±0.00 0.027±0.02 0.600±0.00 N/A N/A
ENST00000549444 N/A 0.230±0.00 N/A N/A N/A 0.503±0.00 N/A 7.021±0.00 0.091±0.00 N/A N/A 2.289±1.64 0.234±0.03 0.823±0.00
ENST00000551051 N/A N/A N/A 0.953±0.00 0.366±0.00 N/A N/A N/A N/A N/A N/A 0.618±0.00 N/A 0.369±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005UQ CIL_0005UQ_0002 CGP 12:113056709-113136239

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005099 IBA Ras GTPase activator activity
GO:0005515 IEA protein binding
GO:0005543 TAS phospholipid binding
GO:0005622 IEA intracellular
GO:0005737 IBA cytoplasm
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0007165 TAS:IEA signal transduction
GO:0031235 IBA intrinsic component of the cytoplasmic side of the plasma membrane
GO:0032318 IEA regulation of Ras GTPase activity
GO:0032320 IBA positive regulation of Ras GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0046580 IBA negative regulation of Ras protein signal transduction
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041515 CU694486.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000089380 RAS protein activator like 1 (GAP1 like) protein_coding Danio_rerio
ENSMUSG00000029602 Rasal1 RAS protein activator like 1 (GAP1 like) protein_coding Mus_musculus

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