C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanine nucleotide binding protein (G protein), beta polypeptide 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111664 GNB3 9606 + 12:6839954-6847393 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000229264 GNB3-002 6840211-6847393 protein_coding
  ENST00000435982 GNB3-005 6840974-6846898 protein_coding
  ENST00000537035 GNB3-009 6841286-6845803 protein_coding
  ENST00000539127 GNB3-008 6840995-6843485 nonsense_mediated_decay
  ENST00000540458 GNB3-003 6839954-6847393 retained_intron
  ENST00000541257 GNB3-007 6840386-6843978 protein_coding
  ENST00000541978 GNB3-011 6840800-6843977 protein_coding
  ENST00000542751 GNB3-010 6845367-6847352 retained_intron
  ENST00000542868 GNB3-004 6841041-6843001 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastHeartLungMuscleOvaryENST00000229264ENST00000435982ENST00000540458ENST00000541257ENST00000542751
Transcript ID Bladder Brain Breast Heart Lung Muscle Ovary
ENST00000229264 N/A N/A N/A 0.588±0.00 1.028±0.00 N/A 1.987±0.00
ENST00000435982 N/A N/A N/A N/A 0.372±0.00 N/A N/A
ENST00000540458 N/A 0.686±0.00 0.168±0.00 N/A N/A N/A 1.816±0.34
ENST00000541257 0.253±0.00 N/A N/A N/A N/A N/A N/A
ENST00000542751 N/A 0.215±0.00 0.814±0.00 N/A N/A 0.079±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003XS CIL_0003XS_0002 CGP 12:6828410-6847393

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 TAS GTPase activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006184 TAS GTP catabolic process
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0008217 TAS regulation of blood pressure
GO:0030507 IEA spectrin binding
GO:0043005 IEA neuron projection
GO:0044281 TAS small molecule metabolic process
GO:0044297 IEA cell body
GO:0051020 IPI GTPase binding
GO:0070062 IDA extracellular vesicular exosome
GO:0071377 TAS cellular response to glucagon stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002696 gnb3b guanine nucleotide binding protein (G protein), beta polypeptide 3b protein_coding Danio_rerio
ENSDARG00000004358 gnb3a guanine nucleotide binding protein (G protein), beta polypeptide 3a protein_coding Danio_rerio
ENSMUSG00000023439 Gnb3 guanine nucleotide binding protein (G protein), beta 3 protein_coding Mus_musculus

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