C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peroxisome proliferator-activated receptor delta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112033 PPARD 9606 + 6:35342558-35428191 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000311565 PPARD-002 35342614-35428178 protein_coding
  ENST00000337400 PPARD-003 35342614-35425393 protein_coding
  ENST00000360694 PPARD-201 35342558-35428191 protein_coding
  ENST00000418635 PPARD-202 35342558-35428191 protein_coding
  ENST00000448077 PPARD-203 35342558-35428191 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000311565ENST00000337400ENST00000360694ENST00000418635ENST00000448077
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000311565 N/A N/A 2.203±0.00 N/A N/A N/A N/A N/A N/A N/A 0.231±0.00 N/A N/A
ENST00000337400 N/A N/A N/A 0.265±0.00 N/A N/A 0.109±0.00 N/A N/A N/A N/A N/A N/A
ENST00000360694 11.908±0.00 13.835±0.00 5.798±4.50 3.919±3.51 7.634±0.00 2.149±1.90 7.459±0.00 3.295±2.32 11.161±10.50 12.040±0.00 8.399±9.25 14.951±4.68 9.405±2.80
ENST00000418635 N/A N/A N/A N/A 0.397±0.00 N/A N/A N/A N/A N/A 3.652±0.00 N/A N/A
ENST00000448077 N/A 3.558±0.00 0.545±0.00 1.316±0.00 3.270±0.00 1.196±0.00 2.021±1.59 1.745±0.00 N/A 1.318±0.00 1.796±0.09 5.637±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008UQ CIL_0008UQ_0001 VISTA 6:35189352-35792826
CIL_0004LU CIL_0004LU_0002 CGP 6:35297852-35428191
CIL_0002EQ CIL_0002EQ_0001 CGP 6:35342558-35467103

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001890 IEA placenta development
GO:0003677 ISS DNA binding
GO:0003700 NAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003713 IEA transcription coactivator activity
GO:0004879 IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005504 IEA fatty acid binding
GO:0005515 IPI protein binding
GO:0005634 NAS:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006006 NAS glucose metabolic process
GO:0006029 IEA proteoglycan metabolic process
GO:0006091 TAS generation of precursor metabolites and energy
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006629 ISS lipid metabolic process
GO:0006635 ISS fatty acid beta-oxidation
GO:0006776 IEA vitamin A metabolic process
GO:0007507 IEA heart development
GO:0007566 TAS embryo implantation
GO:0008144 IDA drug binding
GO:0008203 TAS cholesterol metabolic process
GO:0008270 IEA zinc ion binding
GO:0008283 ISS cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0008289 IDA lipid binding
GO:0008366 ISS axon ensheathment
GO:0008654 IEA phospholipid biosynthetic process
GO:0009062 TAS fatty acid catabolic process
GO:0009299 IEA mRNA transcription
GO:0009749 IEA response to glucose
GO:0010033 IEA response to organic substance
GO:0010467 TAS gene expression
GO:0014068 IEA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014823 IEA response to activity
GO:0014912 IEA negative regulation of smooth muscle cell migration
GO:0015758 NAS glucose transport
GO:0015908 ISS fatty acid transport
GO:0019395 IEA fatty acid oxidation
GO:0030154 IEA cell differentiation
GO:0030308 IEA negative regulation of cell growth
GO:0030522 IEA intracellular receptor signaling pathway
GO:0031589 IEA cell-substrate adhesion
GO:0032024 IEA positive regulation of insulin secretion
GO:0032966 IEA negative regulation of collagen biosynthetic process
GO:0033189 IEA response to vitamin A
GO:0042060 IEA wound healing
GO:0042127 IEA regulation of cell proliferation
GO:0043066 IEA negative regulation of apoptotic process
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0043616 IEA keratinocyte proliferation
GO:0045598 IEA regulation of fat cell differentiation
GO:0045600 NAS positive regulation of fat cell differentiation
GO:0045684 IEA positive regulation of epidermis development
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045909 IEA positive regulation of vasodilation
GO:0046697 TAS decidualization
GO:0048662 IEA negative regulation of smooth muscle cell proliferation
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0050728 IEA negative regulation of inflammatory response
GO:0051059 IEA NF-kappaB binding
GO:0051546 IEA keratinocyte migration
GO:0060612 IEA adipose tissue development
GO:0070539 IDA linoleic acid binding
GO:0071456 IEA cellular response to hypoxia
GO:0097190 IMP apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009473 ppardb peroxisome proliferator-activated receptor delta b protein_coding Danio_rerio
ENSDARG00000044525 pparda peroxisome proliferator-activated receptor delta a protein_coding Danio_rerio
ENSMUSG00000002250 Ppard peroxisome proliferator activator receptor delta protein_coding Mus_musculus

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