C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aldehyde dehydrogenase 5 family, member A1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112294 ALDH5A1 9606 + 6:24494852-24537207 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000348925 ALDH5A1-002 24494969-24534303 protein_coding
  ENST00000357578 ALDH5A1-001 24494852-24537207 protein_coding
  ENST00000479394 ALDH5A1-005 24522638-24534057 retained_intron
  ENST00000491546 ALDH5A1-003 24494867-24533757 protein_coding
  ENST00000492697 ALDH5A1-006 24532010-24533808 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000357578
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000357578 2.650±0.00 1.622±0.00 3.169±0.00 8.092±4.41 3.362±1.50 1.316±0.51 4.816±2.97 7.643±4.81 6.865±6.13 4.950±0.00 2.855±1.17 2.282±0.80 2.095±0.04

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004777 ISS succinate-semialdehyde dehydrogenase (NAD+) activity
GO:0005739 ISS mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006006 ISS glucose metabolic process
GO:0006083 ISS acetate metabolic process
GO:0006105 ISS succinate metabolic process
GO:0006536 ISS glutamate metabolic process
GO:0006541 ISS glutamine metabolic process
GO:0006650 ISS glycerophospholipid metabolic process
GO:0006678 IEA glucosylceramide metabolic process
GO:0006681 ISS galactosylceramide metabolic process
GO:0006749 ISS glutathione metabolic process
GO:0007268 TAS synaptic transmission
GO:0007269 TAS neurotransmitter secretion
GO:0007417 IMP central nervous system development
GO:0008152 IEA metabolic process
GO:0009013 IEA succinate-semialdehyde dehydrogenase [NAD(P)+] activity
GO:0009448 IEA gamma-aminobutyric acid metabolic process
GO:0009450 IEA gamma-aminobutyric acid catabolic process
GO:0009791 IEA post-embryonic development
GO:0016491 IEA oxidoreductase activity
GO:0022904 ISS respiratory electron transport chain
GO:0042135 ISS neurotransmitter catabolic process
GO:0042803 IC protein homodimerization activity
GO:0046459 ISS short-chain fatty acid metabolic process
GO:0051289 IDA protein homotetramerization
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076544 aldh5a1 aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) protein_coding Danio_rerio
ENSMUSG00000035936 Aldh5a1 aldhehyde dehydrogenase family 5, subfamily A1 protein_coding Mus_musculus

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