C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: geminin, DNA replication inhibitor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112312 GMNN 9606 + 6:24774931-24786099 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000230056 GMNN-001 24774938-24786099 protein_coding
  ENST00000356509 GMNN-002 24774931-24786095 protein_coding
  ENST00000378054 GMNN-003 24775413-24785707 protein_coding
  ENST00000378059 GMNN-006 24776866-24784119 protein_coding
  ENST00000468943 GMNN-005 24774949-24777736 retained_intron
  ENST00000476555 GMNN-004 24775467-24781544 protein_coding
  ENST00000620958 GMNN-201 24775413-24786093 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000230056ENST00000356509ENST00000378054ENST00000620958
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000230056 2.004±0.00 1.207±0.00 0.205±0.00 2.980±0.00 2.736±2.04 4.033±2.34 1.142±0.00 2.497±0.00 1.027±0.27 1.331±0.84 N/A 6.075±3.03 4.406±1.43 8.384±0.32
ENST00000356509 0.626±0.00 0.938±0.00 0.366±0.00 1.726±0.00 0.363±0.00 3.093±0.00 0.497±0.00 6.449±0.00 1.845±0.30 N/A N/A 4.033±1.68 2.605±0.68 4.683±0.28
ENST00000378054 N/A N/A N/A N/A N/A N/A 0.090±0.00 1.514±0.00 N/A 1.032±0.00 N/A 26.904±0.00 20.250±0.00 30.743±0.00
ENST00000620958 0.425±0.00 N/A N/A 0.423±0.00 N/A N/A 0.418±0.00 0.646±0.00 N/A 0.744±0.00 1.971±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0003714 IEA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006275 IEA regulation of DNA replication
GO:0006461 IEA protein complex assembly
GO:0008156 IEA:IDA negative regulation of DNA replication
GO:0009887 IEA organ morphogenesis
GO:0042826 IPI histone deacetylase binding
GO:0045786 IEA:IDA negative regulation of cell cycle
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0070491 IEA repressing transcription factor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035957 gmnn geminin, DNA replication inhibitor protein_coding Danio_rerio
ENSMUSG00000006715 Gmnn geminin protein_coding Mus_musculus

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