C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine kinase 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112655 PTK7 9606 + 6:43076268-43161719 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000230418 PTK7-007 43076342-43161712 nonsense_mediated_decay
  ENST00000230419 PTK7-001 43076268-43161719 protein_coding
  ENST00000345201 PTK7-006 43076342-43161712 protein_coding
  ENST00000349241 PTK7-004 43076342-43161712 protein_coding
  ENST00000352931 PTK7-005 43076342-43161712 protein_coding
  ENST00000461100 PTK7-019 43142377-43145259 nonsense_mediated_decay
  ENST00000461389 PTK7-021 43144300-43161036 nonsense_mediated_decay
  ENST00000470019 PTK7-002 43076333-43161719 nonsense_mediated_decay
  ENST00000470471 PTK7-016 43138553-43141948 retained_intron
  ENST00000471863 PTK7-003 43076339-43133721 protein_coding
  ENST00000473339 PTK7-020 43144299-43159883 protein_coding
  ENST00000476760 PTK7-013 43076307-43129617 protein_coding
  ENST00000481273 PTK7-009 43076814-43161010 protein_coding
  ENST00000481946 PTK7-015 43130591-43139243 protein_coding
  ENST00000487673 PTK7-008 43076369-43161713 retained_intron
  ENST00000489707 PTK7-012 43132526-43161719 protein_coding
  ENST00000490710 PTK7-014 43131714-43132551 retained_intron
  ENST00000493339 PTK7-011 43142348-43146164 retained_intron
  ENST00000494146 PTK7-018 43142377-43145261 nonsense_mediated_decay
  ENST00000497957 PTK7-017 43142379-43145432 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000230419ENST00000345201ENST00000349241ENST00000352931ENST00000461100ENST00000461389ENST00000470019ENST00000473339ENST00000481273ENST00000481946ENST00000487673ENST00000489707ENST00000493339ENST00000497957
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000230419 N/A N/A N/A 0.595±0.00 2.380±0.00 1.531±0.00 N/A 4.247±0.00 0.580±0.00 5.362±4.48 N/A 21.550±17.32 19.704±9.69 3.993±0.00
ENST00000345201 N/A N/A 0.685±0.00 N/A N/A N/A 0.216±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000349241 N/A N/A N/A N/A N/A N/A 0.159±0.00 N/A N/A 4.221±0.00 N/A 9.390±0.00 14.000±0.00 2.833±0.00
ENST00000352931 N/A 0.824±0.00 0.394±0.00 0.225±0.11 N/A 0.661±0.00 N/A N/A 0.203±0.00 N/A N/A N/A 5.493±0.00 3.645±0.00
ENST00000461100 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.441±0.00 N/A N/A N/A
ENST00000461389 N/A N/A N/A N/A N/A 1.172±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000470019 0.845±0.00 0.850±0.00 N/A N/A 1.970±0.00 N/A N/A 2.175±0.00 1.350±0.00 N/A N/A N/A N/A 2.319±0.00
ENST00000473339 N/A N/A N/A N/A N/A N/A 0.145±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000481273 0.550±0.00 N/A N/A N/A 2.354±0.00 0.376±0.00 N/A 0.022±0.00 N/A 0.736±0.00 N/A 3.307±0.00 N/A N/A
ENST00000481946 N/A N/A N/A N/A N/A N/A 0.284±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000487673 N/A 0.361±0.00 N/A 0.089±0.00 N/A N/A N/A N/A 0.298±0.00 1.259±0.00 N/A N/A N/A 1.305±0.00
ENST00000489707 N/A 1.392±0.00 N/A 0.889±0.00 3.417±0.00 2.088±0.00 0.330±0.00 5.344±0.00 0.152±0.00 6.192±0.00 N/A N/A 15.370±4.10 9.141±0.00
ENST00000493339 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.014±0.00 N/A N/A N/A
ENST00000497957 N/A N/A N/A N/A N/A N/A N/A 0.063±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001736 IEA establishment of planar polarity
GO:0001843 IEA neural tube closure
GO:0003401 IEA axis elongation
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 TAS transmembrane receptor protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 IEA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005925 IDA focal adhesion
GO:0006468 IEA protein phosphorylation
GO:0007155 IEA cell adhesion
GO:0007165 TAS signal transduction
GO:0010976 IMP positive regulation of neuron projection development
GO:0016020 IEA membrane
GO:0016477 IMP cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0031532 IMP actin cytoskeleton reorganization
GO:0042060 IEA wound healing
GO:0045198 IEA establishment of epithelial cell apical/basal polarity
GO:0060026 IEA convergent extension
GO:0060070 IMP canonical Wnt signaling pathway
GO:0060484 IEA lung-associated mesenchyme development
GO:0071300 IMP cellular response to retinoic acid
GO:0090103 IEA cochlea morphogenesis
GO:0090179 IEA planar cell polarity pathway involved in neural tube closure

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011863 ptk7a protein tyrosine kinase 7a protein_coding Danio_rerio
ENSMUSG00000023972 Ptk7 PTK7 protein tyrosine kinase 7 protein_coding Mus_musculus

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