C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: meprin A, alpha (PABA peptide hydrolase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112818 MEP1A 9606 + 6:46793390-46839782 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000230588 MEP1A-001 46793390-46839778 protein_coding
  ENST00000611727 MEP1A-201 46793399-46839782 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000230588
Transcript ID Adrenal Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000230588 0.005±0.00 2.086±0.00 5.286±4.11 0.072±0.00 0.021±0.00 0.017±0.00 0.083±0.07 0.614±0.41 0.211±0.00 0.225±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BB CIL_0008BB_0001 VISTA 6:46689530-47290187

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IPI:IEA protein binding
GO:0005615 TAS extracellular space
GO:0005887 TAS integral component of plasma membrane
GO:0006508 IEA proteolysis
GO:0007586 TAS digestion
GO:0008237 IEA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0016020 IEA membrane
GO:0017090 IEA meprin A complex
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029747 mep1a.1 meprin A, alpha, tandem duplicate 1 protein_coding Danio_rerio
ENSMUSG00000023914 Mep1a meprin 1 alpha protein_coding Mus_musculus

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