C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: death-associated protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112977 DAP 9606 - 5:10679230-10761272 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000230895 DAP-001 10679230-10761272 protein_coding
  ENST00000432074 DAP-002 10680434-10761228 protein_coding
  ENST00000508253 DAP-006 10683096-10761225 retained_intron
  ENST00000508646 DAP-003 10748083-10761101 retained_intron
  ENST00000510546 DAP-004 10733772-10761199 processed_transcript
  ENST00000514882 DAP-007 10681091-10761136 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000230895ENST00000432074ENST00000510546
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000230895 25.648±0.00 34.109±0.00 2.875±0.00 7.123±6.06 14.212±7.58 12.198±8.77 12.544±0.00 60.182±0.00 39.824±39.25 27.750±24.74 2.667±2.31 30.837±23.80 52.772±15.01 20.957±11.17
ENST00000432074 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.177±0.00 11.402±0.00 N/A
ENST00000510546 N/A N/A 1.443±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006MM CIL_0006MM_0002 CGP 5:10564330-10761272
CIL_0006ML CIL_0006ML_0002 CGP 5:10679230-11904043

Gene Ontology
GO IDEvidence TypeGO Description
GO:0006914 IEA autophagy
GO:0006915 IGI apoptotic process
GO:0006919 IMP activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010507 IMP negative regulation of autophagy
GO:0032088 IMP negative regulation of NF-kappaB transcription factor activity
GO:0034198 IDA cellular response to amino acid starvation
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0070513 IPI death domain binding
GO:0097190 IMP apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000069 dap death associated protein protein_coding Danio_rerio
ENSMUSG00000039168 Dap death-associated protein protein_coding Mus_musculus

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