C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: IK cytokine, down-regulator of HLA II
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113141 IK 9606 + 5:140647058-140662479 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000417647 IK-001 140647770-140662478 protein_coding
  ENST00000502899 IK-006 140648094-140654728 protein_coding
  ENST00000503332 IK-008 140647829-140653102 nonsense_mediated_decay
  ENST00000507593 IK-009 140647842-140653141 protein_coding
  ENST00000508301 IK-010 140647842-140655993 protein_coding
  ENST00000512827 IK-007 140648314-140651747 retained_intron
  ENST00000513256 IK-005 140647058-140653073 protein_coding
  ENST00000515015 IK-011 140658979-140660885 retained_intron
  ENST00000515592 IK-004 140660155-140662479 retained_intron
  ENST00000523672 IK-013 140647928-140653134 processed_transcript
  ENST00000610522 IK-201 140658736-140662214 protein_coding
  ENST00000613660 IK-202 140647799-140662479 protein_coding
  ENST00000620556 IK-203 140647875-140662479 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000417647ENST00000502899ENST00000507593ENST00000508301ENST00000513256ENST00000610522ENST00000613660ENST00000620556
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000417647 N/A 10.415±0.00 1.652±0.00 4.426±0.00 4.630±0.00 2.188±0.00 2.665±0.00 4.247±0.00 7.308±0.00 5.472±0.00 N/A 30.397±27.40 N/A 21.379±0.00
ENST00000502899 N/A N/A N/A N/A N/A N/A N/A N/A 11.511±0.00 N/A N/A N/A N/A N/A
ENST00000507593 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 44.499±0.00 N/A
ENST00000508301 N/A N/A 2.385±0.00 3.286±0.00 4.611±0.00 4.703±0.00 1.888±0.00 7.803±0.00 N/A 9.447±0.00 2.545±0.00 5.628±0.00 N/A N/A
ENST00000513256 N/A N/A N/A N/A 18.822±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000610522 66.082±0.00 46.989±0.00 3.079±0.00 54.243±0.00 49.624±0.00 37.041±32.18 17.028±0.00 39.403±0.00 17.668±0.00 54.861±0.00 63.726±0.00 45.187±7.38 39.232±17.15 131.071±42.88
ENST00000613660 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.131±0.00 N/A N/A N/A
ENST00000620556 40.365±0.00 29.779±0.00 N/A 16.681±15.24 34.554±0.00 27.070±25.11 16.074±0.00 8.868±0.00 10.215±0.00 35.133±0.00 45.421±0.00 25.789±5.46 26.791±3.26 69.942±0.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006ZH CIL_0006ZH_0001 CGP 5:140647058-140674124

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005615 TAS extracellular space
GO:0005634 IEA nucleus
GO:0006955 TAS immune response
GO:0007267 TAS cell-cell signaling
GO:0042802 IPI identical protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004161 ik IK cytokine protein_coding Danio_rerio
ENSMUSG00000024474 Ik IK cytokine protein_coding Mus_musculus

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