C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heart and neural crest derivatives expressed 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113196 HAND1 9606 - 5:154474972-154478264 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000231121 HAND1-001 154474972-154478264 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonHeartLiverLungOvaryPlacentaTestisENST00000231121
Transcript ID Breast Colon Heart Liver Lung Ovary Placenta Testis
ENST00000231121 1.637±0.00 15.070±14.06 5.183±4.53 0.728±0.00 0.036±0.00 0.034±0.00 1.347±0.39 0.440±0.30

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009C8 CIL_0009C8_0001 VISTA 5:153896309-154498445
CIL_00094E CIL_00094E_0001 VISTA 5:153896347-154498404
CIL_00099I CIL_00099I_0001 VISTA 5:154192067-154792416
CIL_00088D CIL_00088D_0001 VISTA 5:154298500-154906275
CIL_0001UK CIL_0001UK_0001 CGP 5:154445957-154478264
CIL_00023W CIL_00023W_0001 CGP 5:154474972-154817607

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001525 ISS angiogenesis
GO:0001701 IEA in utero embryonic development
GO:0001707 IEA mesoderm formation
GO:0001824 IEP blastocyst development
GO:0001829 IEP trophectodermal cell differentiation
GO:0001947 ISS heart looping
GO:0003144 IEA embryonic heart tube formation
GO:0003218 IMP cardiac left ventricle formation
GO:0003219 IMP cardiac right ventricle formation
GO:0003677 IEA DNA binding
GO:0003713 IDA transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IEA nucleoplasm
GO:0005730 IEA nucleolus
GO:0005737 IDA cytoplasm
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007507 ISS heart development
GO:0008134 IPI transcription factor binding
GO:0019899 IEA enzyme binding
GO:0030154 IEA cell differentiation
GO:0035050 ISS embryonic heart tube development
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0042802 ISS identical protein binding
GO:0042803 NAS protein homodimerization activity
GO:0043425 IPI bHLH transcription factor binding
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060411 IMP cardiac septum morphogenesis
GO:0060485 IEA mesenchyme development
GO:0060536 IEA cartilage morphogenesis
GO:0060707 IEA trophoblast giant cell differentiation
GO:0061371 IEA determination of heart left/right asymmetry

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000037335 Hand1 heart and neural crest derivatives expressed transcript 1 protein_coding Mus_musculus

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