C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113525 IL5 9606 - 5:132541444-132556838 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000231454 IL5-001 132541444-132543522 protein_coding
  ENST00000450655 IL5-002 132542066-132556838 protein_coding
  ENST00000462418 IL5-003 132542066-132543920 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartLungOvaryTestisENST00000231454ENST00000450655ENST00000462418
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Lung Ovary Testis
ENST00000231454 N/A 0.041±0.00 N/A 0.084±0.00 N/A 0.092±0.00 N/A 0.089±0.06 1.129±0.19
ENST00000450655 0.213±0.00 N/A N/A N/A N/A N/A N/A N/A 0.889±0.00
ENST00000462418 N/A 0.016±0.00 0.736±0.00 N/A 0.027±0.00 0.310±0.00 0.211±0.00 0.059±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093D CIL_00093D_0001 VISTA 5:131965137-132566411
CIL_0007RF CIL_0007RF_0001 VISTA 5:131967147-132570227

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005125 IEA cytokine activity
GO:0005137 IEA interleukin-5 receptor binding
GO:0005515 IPI protein binding
GO:0005576 IDA:IEA extracellular region
GO:0005615 TAS extracellular space
GO:0006954 IEA inflammatory response
GO:0006955 IEA immune response
GO:0008083 IEA growth factor activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0030890 IEA positive regulation of B cell proliferation
GO:0045645 IEA positive regulation of eosinophil differentiation
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0046427 IEA positive regulation of JAK-STAT cascade
GO:0050731 ISS positive regulation of peptidyl-tyrosine phosphorylation
GO:0051024 IEA positive regulation of immunoglobulin secretion
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0071803 IDA positive regulation of podosome assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000036117 Il5 interleukin 5 protein_coding Mus_musculus

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