C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histamine receptor H2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113749 HRH2 9606 + 5:175658030-175686242 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000231683 HRH2-002 175683234-175684313 protein_coding
  ENST00000377291 HRH2-001 175658030-175686242 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000231683ENST00000377291
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000231683 1.459±0.00 1.946±0.00 N/A 2.370±0.54 0.436±0.00 0.240±0.00 5.358±3.95 0.416±0.00 0.096±0.06 1.267±0.05 0.071±0.00 0.369±0.08 2.433±0.21 0.757±0.00
ENST00000377291 0.868±0.00 1.092±0.00 0.049±0.00 0.721±0.47 0.237±0.03 0.257±0.10 3.818±0.00 0.136±0.01 0.050±0.01 1.307±0.62 N/A 0.137±0.11 0.972±0.00 0.157±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006Z4 CIL_0006Z4_0001 CGP 5:175477062-175686242
CIL_0001QU CIL_0001QU_0001 CGP 5:175658030-175884020

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001696 IEA gastric acid secretion
GO:0001697 IEA histamine-induced gastric acid secretion
GO:0001698 IEA gastrin-induced gastric acid secretion
GO:0003382 IEA epithelial cell morphogenesis
GO:0004930 IEA G-protein coupled receptor activity
GO:0004969 IEA histamine receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006955 TAS immune response
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007187 TAS G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007613 IEA memory
GO:0008542 IEA visual learning
GO:0016021 IEA integral component of membrane
GO:0045907 IEA positive regulation of vasoconstriction
GO:0048167 IEA regulation of synaptic plasticity
GO:0048565 IEA digestive tract development
GO:0048732 IEA gland development
GO:1901998 IEA toxin transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057479 HRH2 histamine receptor H2 protein_coding Danio_rerio
ENSMUSG00000034987 Hrh2 histamine receptor H2 protein_coding Mus_musculus

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