C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kininogen 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113889 KNG1 9606 + 3:186717276-186743954 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265023 KNG1-002 186717331-186743619 protein_coding
  ENST00000287611 KNG1-001 186717276-186743954 protein_coding
  ENST00000447445 KNG1-004 186717348-186743805 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265023ENST00000287611ENST00000447445
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265023 0.048±0.00 0.024±0.00 13.037±0.00 0.040±0.00 0.203±0.00 N/A 75.424±50.33 47.225±47.21 0.015±0.00 N/A 0.538±0.63 0.057±0.00 0.039±0.00
ENST00000287611 N/A N/A 32.704±0.00 0.303±0.00 0.740±0.00 N/A 274.081±172.01 306.917±0.00 N/A N/A 1.971±1.15 0.113±0.02 0.137±0.00
ENST00000447445 N/A N/A N/A 0.226±0.00 N/A 0.030±0.00 57.932±0.00 47.417±47.41 N/A 0.044±0.04 N/A 0.113±0.02 0.247±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008LA CIL_0008LA_0001 VISTA 3:186647123-187250687
CIL_000043 CIL_000043_0001 CGP 3:186660216-186743954
CIL_000042 CIL_000042_0001 CGP 3:186717276-186789900

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002576 TAS platelet degranulation
GO:0004869 IDA:IEA cysteine-type endopeptidase inhibitor activity
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0006939 TAS smooth muscle contraction
GO:0006954 TAS inflammatory response
GO:0007162 IDA negative regulation of cell adhesion
GO:0007204 IDA positive regulation of cytosolic calcium ion concentration
GO:0007596 TAS blood coagulation
GO:0007597 TAS blood coagulation, intrinsic pathway
GO:0008201 NAS heparin binding
GO:0008270 NAS zinc ion binding
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0030168 TAS platelet activation
GO:0030195 IDA negative regulation of blood coagulation
GO:0031093 TAS platelet alpha granule lumen
GO:0035810 TAS positive regulation of urine volume
GO:0035815 TAS positive regulation of renal sodium excretion
GO:0042311 IEA vasodilation
GO:0043065 NAS positive regulation of apoptotic process
GO:0045861 IDA negative regulation of proteolysis
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022372 kng1 kininogen 1 protein_coding Danio_rerio
ENSMUSG00000022875 Kng1 kininogen 1 protein_coding Mus_musculus
ENSMUSG00000060459 Kng2 kininogen 2 protein_coding Mus_musculus

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