C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114279 FGF12 9606 - 3:192139395-192767764 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000418610 FGF12-005 192170564-192727525 protein_coding
  ENST00000430714 FGF12-006 192143988-192727500 protein_coding
  ENST00000440901 FGF12-008 192143599-192268749 protein_coding
  ENST00000445105 FGF12-002 192139395-192727599 protein_coding
  ENST00000448795 FGF12-007 192144060-192727541 protein_coding
  ENST00000450716 FGF12-009 192143978-192767764 protein_coding
  ENST00000454309 FGF12-001 192142509-192409049 protein_coding
  ENST00000466144 FGF12-004 192672966-192727587 processed_transcript
  ENST00000491636 FGF12-003 192726882-192727587 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000430714ENST00000440901ENST00000445105ENST00000448795ENST00000454309
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000430714 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.662±0.00 N/A N/A N/A
ENST00000440901 0.238±0.00 N/A N/A 0.293±0.00 0.459±0.00 N/A N/A 0.310±0.00 0.860±0.00 N/A 0.630±0.00 1.524±1.26 N/A
ENST00000445105 N/A 0.031±0.00 4.499±0.00 N/A N/A 20.628±4.61 0.068±0.00 N/A 0.101±0.02 0.024±0.00 0.014±0.00 0.058±0.06 N/A
ENST00000448795 N/A N/A N/A N/A 0.950±0.00 N/A N/A N/A 1.015±0.00 N/A 0.725±0.00 N/A N/A
ENST00000454309 N/A 0.416±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.110±0.01 0.285±0.07 0.575±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003O5 CIL_0003O5_0002 CGP 3:192139395-192918161

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003254 IEA regulation of membrane depolarization
GO:0005515 IEA protein binding
GO:0005615 TAS extracellular space
GO:0005634 IDA nucleus
GO:0007165 TAS signal transduction
GO:0007254 IPI JNK cascade
GO:0007267 TAS cell-cell signaling
GO:0007268 IEA synaptic transmission
GO:0007399 TAS nervous system development
GO:0007507 TAS heart development
GO:0008083 IEA growth factor activity
GO:0008201 IDA heparin binding
GO:0008344 IEA adult locomotory behavior
GO:0008543 IEA fibroblast growth factor receptor signaling pathway
GO:0010765 IEA positive regulation of sodium ion transport
GO:0017080 ISS sodium channel regulator activity
GO:0044325 ISS ion channel binding
GO:0050905 IEA neuromuscular process
GO:0086002 NAS cardiac muscle cell action potential involved in contraction
GO:1902305 ISS regulation of sodium ion transmembrane transport
GO:2000649 ISS regulation of sodium ion transmembrane transporter activity
GO:2001258 IEA negative regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027957 fgf12a fibroblast growth factor 12a protein_coding Danio_rerio
ENSDARG00000062542 fgf12b fibroblast growth factor 12b protein_coding Danio_rerio
ENSMUSG00000022523 Fgf12 fibroblast growth factor 12 protein_coding Mus_musculus

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